Evidence map›Paper›PMID 37007359›Full record

ReviewCureus2023

Neurological, Psychiatric, and Multisystemic Involvement of Fragile X Syndrome Along With Its Pathophysiology, Methods of Screening, and Current Treatment Modalities.

Raunak Ranjan, Saumya Jha, Priyadarshi Prajjwal, Ansh Chaudhary, Pragya Dudeja, Neel Vora, Mohammed A Mateen, Mohammed A Yousuf, Bhupendra Chaudhary

Open access · diamondFull text readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Genes · 2025
    Article
  3. Review
  4. Review
  5. Review
  6. Epigenetic insights into Fragile X Syndrome.Frontiers in cell and developmental biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Raunak RanjanInternal Medicine, Bharati Vidyapeeth University Medical College, Pune, IND.
Saumya JhaInternal Medicine, Bharati Vidyapeeth University Medical College, Pune, IND.
Priyadarshi PrajjwalNeurology, Bharati Vidyapeeth University Medical College, Pune, IND.
Ansh ChaudharyInternal Medicine, Kasturba Medical College, Manipal, Manipal, IND.
Pragya DudejaInternal Medicine, Bharati Vidyapeeth University Medical College, Pune, IND.
Neel VoraInternal Medicine, B.J. (Byramjee Jeejeebhoy) Medical College, Ahmedabad, IND.
Mohammed A MateenInternal Medicine, Shadan Institute of Medical Sciences Teaching Hospital and Research Centre, Hyderabad, IND.
Mohammed A YousufInternal Medicine, Shadan Institute of Medical Sciences Teaching Hospital and Research Centre, Hyderabad, IND.
Bhupendra ChaudharyNeuroscience, Jaswant Rai Speciality Hospital, Meerut, IND.
B. J. Medical College & Sassoon Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fragile X syndrome (FXS) is a hereditary disease that predominantly leads to intellectual disability (ID) in boys. It is the second prominent cause of ID, which manifests as a result of the atypical development of the cytosine-guanine-guanine (CGG) region. This irregular extension of the CGG region gives rise to methylation and silencing of the fragile X mental retardation 1 (

Indexed as

autismautism spectrum disorder (asd)cgg repeatsconnective tissue disorder(ctd)fmr1 genefragile x mental retardation 1fragile x syndromeintellectual disability (id)neuropsychiatric

Identifiers

PMID37007359
PMCPMC10050793
OpenAlexW4322216826

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read29
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.