Evidence map›Paper›PMID 37007288›Full record

ArticleJournal of pharmacopuncture2023

The Chronic and Acute Toxicity of Traditional Medicines Containing

Arongqiqige, Gerelmaa Enebish, Wang Song, Wei Cheng Xi, Anuujin Gantumur, Oyunbaatar Altanbayar, Hirofumi Shimomura, Battogtokh Chimeddorj, Batnairamdal Chuluun, Avarzed Amgalanbaatar

Open access · diamondAbstract read
In one paragraph

Article in Journal of pharmacopuncture, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

ArongqiqigeDepartment of Microbiology and Infection Prevention Control, School of Biomedicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.ORCID https://orcid.org/0000-0001-5093-0722
Gerelmaa EnebishDepartment of Microbiology and Infection Prevention Control, School of Biomedicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.ORCID https://orcid.org/0000-0003-0638-0895
Wang SongInner Mongolia Autonomous Region Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Inner Mongolia Minzu University, Tongliao, Inner Mongolia, China.ORCID https://orcid.org/0000-0002-3379-4316
Wei Cheng XiInner Mongolia Autonomous Region Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Inner Mongolia Minzu University, Tongliao, Inner Mongolia, China.ORCID https://orcid.org/0000-0001-7707-9499
Anuujin GantumurDepartment of Microbiology and Infection Prevention Control, School of Biomedicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.ORCID https://orcid.org/0000-0002-5594-3597
Oyunbaatar AltanbayarDepartment of Microbiology and Infection Prevention Control, School of Biomedicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.ORCID https://orcid.org/0000-0001-6400-7111
Hirofumi ShimomuraDepartment of Organoid Research, KBBM Ltd., Kyoto, Japan.ORCID https://orcid.org/0000-0002-1000-3673
Battogtokh ChimeddorjDepartment of Microbiology and Infection Prevention Control, School of Biomedicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.ORCID https://orcid.org/0000-0002-5299-2406
Batnairamdal ChuluunDepartment of Internal Medicine, International School of Mongolian Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.ORCID https://orcid.org/0000-0003-3659-7825
Avarzed AmgalanbaatarInternational Cyber Education Center, Graduate School, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.ORCID https://orcid.org/0000-0002-1667-0813
Mongolian National University · MN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Methods: Acute and chronic toxicity of Altan Arur 5 were assessed in 10 Kunming mice and 8 Sprague-Dawley rats, respectively, in different doses. In the acute toxicity study, Altan Arur 5 was orally administered to Kunming mice in doses of 12 g/kg, 24 g/kg, and 48 g/kg for 14 days. In the chronic toxicity study, it was orally administered to Sprague-Dawley rats in doses of 1.25 g/kg, 2.5 g/kg, and 5 g/kg for 12 weeks. Results: No significant differences were observed in the relative organ weights for mice treated with Altan Arur 5 compared with those in the control group. Furthermore, no macro- or microstructural changes were noted in the organs of any group. Conclusion: Our toxicity testing revealed that the traditional medicine Altan Arur 5 has no toxic effects in vivo.

Indexed as

acute toxicityaltan arur 5chronic toxicitypunica granatumterminalia chebulatraditional medicine

Identifiers

PMID37007288
PMCPMC10063424
OpenAlexW4361028132

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.