Evidence map›Paper›PMID 37006925›Full record

ArticleFrontiers in nutrition2023

The impact of preoperative nutritional screening, ERAS protocol, and mini-invasive surgery in surgical oncology: A multi-institutional SEM analysis of patients with digestive cancer.

Laura Lorenzon, Riccardo Caccialanza, Valentina Casalone, Gloria Santoro, Paolo Delrio, Francesco Izzo, Marco Tonello, Maria Cristina Mele, Carmelo Pozzo, Paolo Pedrazzoli and 20 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Sarcopenia in Colorectal Cancer Surgery-Minimally Invasive vs. Open.Journal of cachexia, sarcopenia and muscle · 2025
    Article
  2. Article
  3. Review
  4. A study on the effect of nutrition education based on the goal attainment theory on oral nutritional supplementation after colorectal cancer surgery.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 6 institutions in 1 country.

Laura LorenzonFondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.
Riccardo CaccialanzaFondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Valentina CasaloneCandiolo Cancer Institute-IRCCS, Turin, Italy.
Gloria SantoroFondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.
Paolo DelrioIstituto Nazionale per lo Studio e la Cura dei Tumori Fondazione Giovanni Pascale IRCCS, Naples, Italy.
Francesco IzzoIstituto Nazionale per lo Studio e la Cura dei Tumori Fondazione Giovanni Pascale IRCCS, Naples, Italy.
Marco TonelloVeneto Institute of Oncology IOV-IRCCS, Padua, Italy.
Maria Cristina MeleFondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.
Carmelo PozzoFondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.
Paolo PedrazzoliFondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Andrea PietrabissaFondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Piero FenuCandiolo Cancer Institute-IRCCS, Turin, Italy.
Alfredo MellanoCandiolo Cancer Institute-IRCCS, Turin, Italy.
Elisabetta FenocchioCandiolo Cancer Institute-IRCCS, Turin, Italy.
Antonio AvalloneIstituto Nazionale per lo Studio e la Cura dei Tumori Fondazione Giovanni Pascale IRCCS, Naples, Italy.
Francesca BergamoVeneto Institute of Oncology IOV-IRCCS, Padua, Italy.
Maria Teresa NardiVeneto Institute of Oncology IOV-IRCCS, Padua, Italy.
Roberto PersianiFondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.
Alberto BiondiFondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.
Flavio TirelliFondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.
Annamaria AgnesFondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.
Renato FerrarisCandiolo Cancer Institute-IRCCS, Turin, Italy.
Virginia QuaràCandiolo Cancer Institute-IRCCS, Turin, Italy.
Michela MilanesioCandiolo Cancer Institute-IRCCS, Turin, Italy.
Dario RiberoCandiolo Cancer Institute-IRCCS, Turin, Italy.
Marilena RinaldiCandiolo Cancer Institute-IRCCS, Turin, Italy.
Paola D'EliaCandiolo Cancer Institute-IRCCS, Turin, Italy.
Maurizio RhoIstituto Nazionale per lo Studio e la Cura dei Tumori Fondazione Giovanni Pascale IRCCS, Naples, Italy.
Carola CenziVeneto Institute of Oncology IOV-IRCCS, Padua, Italy.
Domenico D'UgoFondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome, Italy.
Candiolo Cancer Institute · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITAgostino Gemelli University Polyclinic · ITIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITPoliclinico San Matteo Fondazione · ITIstituto Oncologico Veneto · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mini-invasive surgery (MIS), ERAS, and preoperative nutritional screening are currently used to reduce complications and the length of hospital stay (LOS); however, inter-variable correlations have seldom been explored. This research aimed to define inter-variable correlations in a large series of patients with gastrointestinal cancer and their impact on outcomes. Methods: Patients with consecutive cancer who underwent radical gastrointestinal surgery between 2019 and 2020 were analyzed. Age, BMI, comorbidities, ERAS, nutritional screening, and MIS were evaluated to determine their impact on 30-day complications and LOS. Inter-variable correlations were measured, and a latent variable was computed to define the patients' Results: Of the 1,968 eligible patients, 1,648 were analyzed. Univariable analyses documented the benefit of nutritional screening for LOS and MIS and ERAS (≥7 items) for LOS and complications; conversely, being male and comorbidities correlated with complications, while increased age and BMI correlated with worse outcomes. SEM analysis revealed that (a) the latent variable is explained by the use of nutritional screening (p0·004); (b) the variables were correlated (age-comorbidity, ERAS-MIS, and ERAS-nutritional screening, Conclusion: Enhanced recovery after surgery (ERAS), MIS, and nutritional screening are beneficial in surgical oncology; however, the inter-variable correlation is reliable, underlying the importance of the multidisciplinary approach.

Indexed as

digestive cancersmini-invasive surgerynutritional screeningstructural equation modeling (SEM)surgical oncology

Identifiers

PMID37006925
PMCPMC10063158
OpenAlexW4327605911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.