Evidence map›Paper›PMID 37006776›Full record

ArticleJACS Au2023

Revealing the Specificity of Human H1 Influenza A Viruses to Complex

Angeles Canales, Javier Sastre, Jose M Orduña, Cindy M Spruit, Javier Pérez-Castells, Gema Domínguez, Kim M Bouwman, Roosmarijn van der Woude, Francisco Javier Cañada, Corwin M Nycholat and 4 more

Open access · goldAbstract read
In one paragraph

Article in JACS Au, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Virus-Glycan Interactions Studied by Solute NMR.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 3 countries.

Angeles CanalesDepartment of Organic Chemistry, Faculty of Chemistry, Universidad Complutense de Madrid, Avd. Complutense s/n, Madrid 28040, Spain.ORCID https://orcid.org/0000-0003-0542-3080
Javier SastreCentro de Investigaciones Biológicas Margarita Salas, CSIC, C/Ramiro de Maetzu 9, Madrid 28040, Spain.
Jose M OrduñaDepartment of Chemistry and Biochemistry Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities Urbanización Montepríncipe, Boadilla del Monte, Madrid 28660, Spain.ORCID https://orcid.org/0000-0003-4955-4998
Cindy M SpruitDepartment of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht 3584 CG, The Netherlands.
Javier Pérez-CastellsDepartment of Chemistry and Biochemistry Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities Urbanización Montepríncipe, Boadilla del Monte, Madrid 28660, Spain.ORCID https://orcid.org/0000-0002-7256-0723
Gema DomínguezDepartment of Chemistry and Biochemistry Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities Urbanización Montepríncipe, Boadilla del Monte, Madrid 28660, Spain.
Kim M BouwmanDepartment of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht 3584 CG, The Netherlands.
Roosmarijn van der WoudeDepartment of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht 3584 CG, The Netherlands.
Francisco Javier CañadaCentro de Investigaciones Biológicas Margarita Salas, CSIC, C/Ramiro de Maetzu 9, Madrid 28040, Spain.ORCID https://orcid.org/0000-0003-4462-1469
Corwin M NycholatDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, California 92037, United States.
James C PaulsonDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, California 92037, United States.ORCID https://orcid.org/0000-0003-4589-5322
Geert-Jan BoonsDepartment of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht 3584 CG, The Netherlands.
Jesús Jiménez-BarberoCentro de Investigación Biomédica en Red-Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, C/ Monforte de Lemos 3-5, Pabellón 11, Madrid 28029, Spain.ORCID https://orcid.org/0000-0001-5421-8513
Robert P de VriesDepartment of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht 3584 CG, The Netherlands.ORCID https://orcid.org/0000-0002-1586-4464
Utrecht University · NLUniversidad San Pablo CEU · ESScripps Research Institute · USCentro de Investigaciones Biológicas Margarita Salas · ESIkerbasque · ESInstituto de Salud Carlos III · ESUniversidad Complutense de Madrid · ESUniversity of Georgia · US

Funding

Influenza virus receptors on human airway epithelial cellsR01AI114730 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI PAULSON, JAMES C · 2015 to 2023
$5.1M
NIAID NIH HHS R01 AI114730
6 · The paper itself

Abstract

Influenza virus infection remains a threat to human health since viral hemagglutinins are constantly drifting, escaping infection and vaccine-induced antibody responses. Viral hemagglutinins from different viruses display variability in glycan recognition. In this context, recent H3N2 viruses have specificity for α2,6 sialylated branched

Identifiers

PMID37006776
PMCPMC10052259
OpenAlexW4321197435

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.