Evidence map›Paper›PMID 37006695›Full record

ArticleChemical science2023

Real-time monitoring of the sialic acid biosynthesis pathway by NMR.

Jacob L Gorenflos López, Peter Schmieder, Kristin Kemnitz-Hassanin, Hatice Ceyda Asikoglu, Arif Celik, Christian E Stieger, Dorothea Fiedler, Stephan Hinderlich, Christian P R Hackenberger

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  3. Simultaneous ManNAc and Neu5Ac Quantification in Human Sera by LC-MS/MS.International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jacob L Gorenflos LópezLeibniz-Institut für Molekulare Pharmakologie Robert-Roessle-Strasse 10 13125 Berlin Germany hackenbe@fmp-berlin.de.ORCID https://orcid.org/0000-0001-6485-3780
Peter SchmiederLeibniz-Institut für Molekulare Pharmakologie Robert-Roessle-Strasse 10 13125 Berlin Germany hackenbe@fmp-berlin.de.ORCID https://orcid.org/0000-0001-9968-9327
Kristin Kemnitz-HassaninLeibniz-Institut für Molekulare Pharmakologie Robert-Roessle-Strasse 10 13125 Berlin Germany hackenbe@fmp-berlin.de.
Hatice Ceyda AsikogluLeibniz-Institut für Molekulare Pharmakologie Robert-Roessle-Strasse 10 13125 Berlin Germany hackenbe@fmp-berlin.de.
Arif CelikLeibniz-Institut für Molekulare Pharmakologie Robert-Roessle-Strasse 10 13125 Berlin Germany hackenbe@fmp-berlin.de.
Christian E StiegerLeibniz-Institut für Molekulare Pharmakologie Robert-Roessle-Strasse 10 13125 Berlin Germany hackenbe@fmp-berlin.de.ORCID https://orcid.org/0000-0001-5829-2307
Dorothea FiedlerLeibniz-Institut für Molekulare Pharmakologie Robert-Roessle-Strasse 10 13125 Berlin Germany hackenbe@fmp-berlin.de.ORCID https://orcid.org/0000-0002-0798-946X
Stephan HinderlichBerliner Hochschule für Technik, Department Life Sciences & Technology Seestrasse 64 13347 Berlin Germany.
Christian P R HackenbergerLeibniz-Institut für Molekulare Pharmakologie Robert-Roessle-Strasse 10 13125 Berlin Germany hackenbe@fmp-berlin.de.ORCID https://orcid.org/0000-0001-7457-4742
Humboldt-Universität zu Berlin · DEBerliner Hochschule für Technik · DELeibniz-Forschungsinstitut für Molekulare Pharmakologie · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sialic acids are part of the outermost component of the glycocalyx of all vertebrates; as such, they are fundamental markers in physiological and pathological processes. In this study, we introduce a real-time assay to monitor individual enzymatic steps of sialic acid biosynthesis, either with recombinant enzymes, in particular using UDP-

Identifiers

PMID37006695
PMCPMC10055903
OpenAlexW4321444028

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.