Evidence map›Paper›PMID 37006687›Full record

ArticleChemical science2023

Supramolecular photosensitizers using extended macrocyclic hosts for photodynamic therapy with distinct cellular delivery.

Xiuli Zheng, Sheng-Nan Lei, Zekun Gao, Xiangyu Dong, Hongyan Xiao, Weimin Liu, Chen-Ho Tung, Li-Zhu Wu, Pengfei Wang, Huan Cong

Abstract read
In one paragraph

Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiuli ZhengKey Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, School of Future Technology, University of Chinese Academy of Sciences, Chinese Academy of Sciences Beijing 100190 China wmliu@mail.ipc.ac.cn wangpf@mail.ipc.ac.cn hcong@mail.ipc.ac.cn.ORCID https://orcid.org/0000-0002-1369-3665
Sheng-Nan LeiKey Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, School of Future Technology, University of Chinese Academy of Sciences, Chinese Academy of Sciences Beijing 100190 China wmliu@mail.ipc.ac.cn wangpf@mail.ipc.ac.cn hcong@mail.ipc.ac.cn.
Zekun GaoKey Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, School of Future Technology, University of Chinese Academy of Sciences, Chinese Academy of Sciences Beijing 100190 China wmliu@mail.ipc.ac.cn wangpf@mail.ipc.ac.cn hcong@mail.ipc.ac.cn.
Xiangyu DongKey Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, School of Future Technology, University of Chinese Academy of Sciences, Chinese Academy of Sciences Beijing 100190 China wmliu@mail.ipc.ac.cn wangpf@mail.ipc.ac.cn hcong@mail.ipc.ac.cn.
Hongyan XiaoKey Laboratory of Bio-inspired Materials and Interfacial Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences Beijing 100190 China.ORCID https://orcid.org/0000-0003-1058-9149
Weimin LiuKey Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, School of Future Technology, University of Chinese Academy of Sciences, Chinese Academy of Sciences Beijing 100190 China wmliu@mail.ipc.ac.cn wangpf@mail.ipc.ac.cn hcong@mail.ipc.ac.cn.ORCID https://orcid.org/0000-0001-7507-6032
Chen-Ho TungKey Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, School of Future Technology, University of Chinese Academy of Sciences, Chinese Academy of Sciences Beijing 100190 China wmliu@mail.ipc.ac.cn wangpf@mail.ipc.ac.cn hcong@mail.ipc.ac.cn.ORCID https://orcid.org/0000-0001-9999-9755
Li-Zhu WuKey Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, School of Future Technology, University of Chinese Academy of Sciences, Chinese Academy of Sciences Beijing 100190 China wmliu@mail.ipc.ac.cn wangpf@mail.ipc.ac.cn hcong@mail.ipc.ac.cn.ORCID https://orcid.org/0000-0002-5561-9922
Pengfei WangKey Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, School of Future Technology, University of Chinese Academy of Sciences, Chinese Academy of Sciences Beijing 100190 China wmliu@mail.ipc.ac.cn wangpf@mail.ipc.ac.cn hcong@mail.ipc.ac.cn.ORCID https://orcid.org/0000-0002-8233-8798
Huan CongKey Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, School of Future Technology, University of Chinese Academy of Sciences, Chinese Academy of Sciences Beijing 100190 China wmliu@mail.ipc.ac.cn wangpf@mail.ipc.ac.cn hcong@mail.ipc.ac.cn.ORCID https://orcid.org/0000-0003-1687-2404

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The photosensitizers (PSs) for photodynamic therapy (PDT) mostly possess conjugated skeletons that are over-sized and poorly water-soluble to be encapsulated by conventional macrocyclic receptors. Herein, we report that two fluorescent hydrophilic cyclophanes, AnBox·4Cl and ExAnBox·4Cl, can effectively bind hypocrellin B (HB), a pharmaceutically active natural PS for PDT, with binding constants of the 10

Identifiers

PMID37006687
PMCPMC10055832

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.