Evidence map›Paper›PMID 37006671›Full record

ArticleAnalysis & sensing2023

Oxygen-Sensing Chemiluminescent Iridium(III) 1,2-Dioxetanes: Unusual Coordination and Activity.

Husain N Kagalwala, Lorena Bueno, Hashini Wanniarachchi, Daniel K Unruh, Khagendra B Hamal, Cyprian I Pavlich, Graham J Carlson, Kevin G Pinney, Ralph P Mason, Alexander R Lippert

Abstract read
In one paragraph

Article in Analysis & sensing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. A silicon rhodamine 1,2-dioxetane chemiluminophore forOrganic & biomolecular chemistry · 2025
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Husain N KagalwalaDepartment of Chemistry, Southern Methodist University, Dallas, TX 75275-0314 (USA).ORCID 0000-0002-5628-5901
Lorena BuenoPrognostic Imaging Research Laboratory, Pre-clinical Imaging Section, Department of Radiology, UT Southwestern Medical Center, Dallas, TX 75390-9058 (USA).
Hashini WanniarachchiPrognostic Imaging Research Laboratory, Pre-clinical Imaging Section, Department of Radiology, UT Southwestern Medical Center, Dallas, TX 75390-9058 (USA).
Daniel K UnruhX-ray Diffraction Facility, Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061 (USA).ORCID 0000-0002-2594-5786
Khagendra B HamalDepartment of Chemistry and Biochemistry, Baylor University, Waco, TX 76798-7348 (USA).
Cyprian I PavlichDepartment of Chemistry and Biochemistry, Baylor University, Waco, TX 76798-7348 (USA).
Graham J CarlsonDepartment of Chemistry and Biochemistry, Baylor University, Waco, TX 76798-7348 (USA).
Kevin G PinneyDepartment of Chemistry and Biochemistry, Baylor University, Waco, TX 76798-7348 (USA).ORCID 0000-0003-1262-8631
Ralph P MasonPrognostic Imaging Research Laboratory, Pre-clinical Imaging Section, Department of Radiology, UT Southwestern Medical Center, Dallas, TX 75390-9058 (USA).ORCID 0000-0001-7517-3721
Alexander R LippertDepartment of Chemistry, Southern Methodist University, Dallas, TX 75275-0314 (USA).ORCID 0000-0003-4396-0848

Funding

UT Southwestern Medical Center Simmons Comprehensive Cancer CenterP30CA142543 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Sandi Leigh Pruitt · 2010 to 2026
$53.7M
Vascular image-guided optimization of response (VIGOR) to therapy in kidney cancerR01CA244579 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI LIU, LI, PINNEY, KEVIN G. · 2020 to 2024
$2.4M
Small Animal Bioluminescence and Fluorescence Imaging System (with 3D capability)S10RR024757 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI MASON, RALPH P. · 2007 to 2007
$335k
NCI NIH HHS P30 CA142543NCI NIH HHS R01 CA244579NCRR NIH HHS S10 RR024757
6 · The paper itself

Abstract

Next generation chemiluminescent iridium 1,2-dioxetane complexes have been developed which consist of the Schaap's 1,2-dioxetane scaffold directly attached to the metal center. This was achieved by synthetically modifying the scaffold precursor with a phenylpyridine moiety, which can act as a ligand. Reaction of this scaffold ligand with the iridium dimer [Ir(BTP)

Indexed as

chemiluminescencein vivo imagingiridium complexesoxygen sensingSchaap dioxetanes

Identifiers

PMID37006671
PMCPMC10061878

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.