Evidence map›Paper›PMID 37006470›Full record

ArticleFrontiers in cellular neuroscience2023

Soluble TNF mediates amyloid-independent, diet-induced alterations to immune and neuronal functions in an Alzheimer's disease mouse model.

Kathryn P MacPherson, Lori N Eidson, Madelyn C Houser, Blaine E Weiss, Jenna L Gollihue, Mary K Herrick, Maria Elizabeth de Sousa Rodrigues, Lindsey Sniffen, Erica M Weekman, Adam M Hamilton and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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  8. Thinking outside the brain: Gut microbiome influence on innate immunity within neurodegenerative disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Kathryn P MacPhersonDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, United States.
Lori N EidsonDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, United States.
Madelyn C HouserDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, United States.
Blaine E WeissSanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, KY, United States.
Jenna L GollihueSanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, KY, United States.
Mary K HerrickDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, United States.
Maria Elizabeth de Sousa RodriguesDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, United States.
Lindsey SniffenDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, United States.
Erica M WeekmanSanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, KY, United States.
Adam M HamiltonDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, United States.
Sean D KellyDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, United States.
Danielle L OliverDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, United States.
Yuan YangDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, United States.
Jianjun ChangDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, United States.
Timothy R SampsonDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, United States.
Christopher M NorrisSanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, KY, United States.
Malú Gámez TanseyDepartment of Physiology, Emory University School of Medicine, Atlanta, GA, United States.
Emory University · USUniversity of Kentucky · USFlorida College · US

Funding

University of Kentucky Alzheimer's Disease Research CenterP30AG072946 · NIA · UNIVERSITY OF KENTUCKY · PI LINDA J VAN ELDIK · 2021 to 2026
$23.5M
Inflammation and Renin-Angiotensin System Dysfunction as risk factors for ADRF1AG051514 · NIA · EMORY UNIVERSITY · PI NORRIS, CHRISTOPHER MARK, WALKER, LARY C · 2015 to 2017
$3.6M
Calcineurin and inflammatory signaling processes in aging and Alzheimer's DiseaseRF1AG027297 · NIA · UNIVERSITY OF KENTUCKY · PI NORRIS, CHRISTOPHER MARK · 2018 to 2022
$2.6M
Role of Gut Inflammation and Immunity on Proteostasis, Noradrenergic Degeneration and AD riskRF1AG057247 · NIA · UNIVERSITY OF FLORIDA · PI NEISH, ANDREW S, TANSEY, MARIA DE LOURDES GAMEZ · 2017 to 2017
$1.6M
NIA NIH HHS P30 AG072946NIA NIH HHS RF1 AG027297NIA NIH HHS RF1 AG051514NIA NIH HHS RF1 AG057247
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer’s diseaseelectrophysiologyflow cytometrymacrophagemicrobiomeneuroinflammationsoluble TNFT cells

Identifiers

PMID37006470
PMCPMC10052573
OpenAlexW4324361249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.