Evidence map›Paper›PMID 37006300›Full record

SynthesisFrontiers in immunology2023

Overlapping cytokines in

Bingting Yu, Luochengling Xiang, Maikel P Peppelenbosch, Gwenny M Fuhler

Open access · goldFull text readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. World journal of gastrointestinal oncology · 2026
    Article
  5. Systemic serological signatures and novel biomarker CST4 link CagA-positiveFrontiers in cellular and infection microbiology · 2026
    Article
  6. Periodontitis and Systemic Health: An Interconnected Relationship.Advances in experimental medicine and biology · 2026
    Review
  7. Article
  8. Update on the pathogenesis and clinical management ofWorld journal of gastrointestinal pathophysiology · 2025
    Review
  9. Prevalence, Risk Factors, and Endoscopic Findings ofAntibiotics (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Association betweenFrontiers in medicine · 2025
    Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Helicobacter pylori upregulates circPGD and promotes development of gastric cancer.Journal of cancer research and clinical oncology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bingting YuDepartment of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, Netherlands.
Luochengling XiangDepartment of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, Netherlands.
Maikel P PeppelenboschDepartment of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, Netherlands.
Gwenny M FuhlerDepartment of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, Netherlands.
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Previous evidence indicated that Methods: We performed a systematic review and tandem meta-analysis identifying all published studies reporting on serum cytokine levels in Results: Only levels of systemic IL-6 (standardized mean difference [SMD]:0.95, 95%CI [0.45;1.45]) and TNF-α (SMD:0.88, 95%CI [0.46; 1.29]) were significantly increased upon Conclusion: This study shows that

Indexed as

Helicobacter InfectionsHelicobacter pyloriStomach NeoplasmsCytokinesHumansInterleukin-6Tumor Necrosis Factor-alphaCytokinesInterleukin-6Tumor Necrosis Factor-alphacytokinesELISAgastric cancerH. pyloriinterleukin-6serum

Identifiers

PMID37006300
PMCPMC10050690
OpenAlexW4324373258

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read44
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.