Evidence map›Paper›PMID 37006283›Full record

ArticleFrontiers in immunology2023

Parasitic nematode secreted phospholipase A

Sophia C Parks, Ogadinma K Okakpu, Pakeeza Azizpor, Susan Nguyen, Stephanie Martinez-Beltran, Isaiah Claudio, Kyle Anesko, Anil Bhatia, Harpal S Dhillon, Adler R Dillman

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The nematode parasitemicroPublication biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sophia C ParksDepartment of Nematology, University of California, Riverside, CA, United States.
Ogadinma K OkakpuDepartment of Nematology, University of California, Riverside, CA, United States.
Pakeeza AzizporDepartment of Nematology, University of California, Riverside, CA, United States.
Susan NguyenDepartment of Nematology, University of California, Riverside, CA, United States.
Stephanie Martinez-BeltranDepartment of Nematology, University of California, Riverside, CA, United States.
Isaiah ClaudioDepartment of Nematology, University of California, Riverside, CA, United States.
Kyle AneskoDepartment of Nematology, University of California, Riverside, CA, United States.
Anil BhatiaMetabolomics Core Facility, IIGB, University of California, Riverside, CA, United States.
Harpal S DhillonDepartment of Nematology, University of California, Riverside, CA, United States.
Adler R DillmanDepartment of Nematology, University of California, Riverside, CA, United States.
University of California, Riverside · US

Funding

UC Riverside MARC U* Star Undergraduate Research ProgramT34GM062756 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI MARTINEZ, ERNEST · 2001 to 2022
$8.7M
Molecular mayhem: Immune modulation and eicosanoid signaling during infectionR35GM137934 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI Adler Ray Dillman · 2020 to 2026
$2.3M
MARC at University of California RiversideT34GM149470 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI ERNEST MARTINEZ · 2023 to 2026
$2.1M
NIGMS NIH HHS R35 GM137934NIGMS NIH HHS T34 GM062756NIGMS NIH HHS T34 GM149470
6 · The paper itself

Abstract

A key aspect of parasitic nematode infection is the nematodes' ability to evade and/or suppress host immunity. This immunomodulatory ability is likely driven by the release of hundreds of excretory/secretory proteins (ESPs) during infection. While ESPs have been shown to display immunosuppressive effects on various hosts, our understanding of the molecular interactions between individual proteins released and host immunity requires further study. We have recently identified a secreted phospholipase A2 (sPLA

Indexed as

NematodaPhospholipases A2, SecretoryAnimalsDrosophila melanogasterHemocytesHost-Parasite InteractionsImmunity, HumoralPhospholipases A2, SecretoryDrosophilahost-parasite interactionsimmune modulationsPLA2Steinernema carpocapsae

Identifiers

PMID37006283
PMCPMC10050561
OpenAlexW4324378446

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read69
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.