Evidence map›Paper›PMID 37005071›Full record

ArticleAmerican journal of epidemiology2023

Use of Chemical Hair Straighteners and Fecundability in a North American Preconception Cohort.

Lauren A Wise, Tanran R Wang, Collette N Ncube, Sharonda M Lovett, Jasmine Abrams, Renée Boynton-Jarrett, Martha R Koenig, Ruth J Geller, Amelia K Wesselink, Chad M Coleman and 2 more

Abstract read
In one paragraph

Article in American journal of epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lauren A Wise
Tanran R Wang
Collette N Ncube
Sharonda M Lovett
Jasmine Abrams
Renée Boynton-Jarrett
Martha R Koenig
Ruth J Geller
Amelia K Wesselink
Chad M Coleman
Elizabeth E Hatch
Tamarra James-Todd

Funding

An internet-based preconception cohort study in North America and DenmarkR01HD086742 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LAUREN A WISE · 2016 to 2026
$6.7M
A preconception cohort study of environmental chemicals, fertility, and miscarriageR01ES029951 · NIEHS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WISE, LAUREN A · 2019 to 2023
$3.1M
Phthalates, Gestational Diabetes, and Markers of Type 2 Diabetes Risk in WomenR01ES026166 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI JAMES-TODD, TAMARRA M · 2016 to 2021
$2.9M
Understanding racial and ethnic disparities in preterm birth: a systems science approachK01MD013911 · NIMHD · NORTHEASTERN UNIVERSITY · PI NCUBE, COLLETTE N · 2019 to 2023
$688k
NICHD NIH HHS R01 HD086742NIEHS NIH HHS R01 ES026166NIEHS NIH HHS R01 ES029951NIMHD NIH HHS K01 MD013911
6 · The paper itself

Abstract

Chemical hair straighteners ("relaxers") are used by millions of North Americans, particularly women of color. Hair relaxers may contain endocrine-disrupting compounds, which can harm fertility. We evaluated the association between hair relaxer use and fecundability among 11,274 participants from Pregnancy Study Online (PRESTO), a North American preconception cohort study. During 2014-2022, participants completed a baseline questionnaire in which they reported their history of relaxer use and completed follow-up questionnaires every 8 weeks for 12 months or until pregnancy, whichever came first. We used multivariable-adjusted proportional probabilities regression models to estimate fecundability ratios (FRs) and 95% confidence intervals (CIs). Relative to never use, fecundability was lower among current (FR = 0.81, 95% CI: 0.64, 1.03) and former (FR = 0.89, 95% CI: 0.81, 0.98) users of hair relaxers. FRs for first use of hair relaxers at ages <10, 10-19, and ≥20 years were 0.73 (95% CI: 0.55, 0.96), 0.93 (95% CI: 0.83, 1.04), and 0.85 (95% CI: 0.74, 0.98), respectively. Fecundability was lowest among those with longer durations of use (≥10 years vs. never: FR = 0.71, 95% CI: 0.54, 0.91) and more frequent use (≥5 times/year vs. never: FR = 0.82, 95% CI: 0.60, 1.11), but associations were nonmonotonic. In this preconception cohort study, use of chemical hair straighteners was associated with slightly reduced fecundability.

Indexed as

FertilityCohort StudiesFemaleHumansNorth AmericaPregnancyProspective StudiesSurveys and Questionnairesendocrine-disrupting chemicalsfemalesfertilityhair straightenersprospective studies

Identifiers

PMID37005071
PMCPMC10505421

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.