Evidence map›Paper›PMID 37004908›Full record

ArticleNeuroscience2023

Dietary Supplementation with Milk Lipids Leads to Suppression of Developmental and Behavioral Phenotypes of Hyperexcitable Drosophila Mutants.

Junko Kasuya, Wayne Johnson, Hung-Lin Chen, Toshihiro Kitamoto

Open access · greenAbstract read
In one paragraph

Article in Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Automated identification of ataxia and convulsions in hyperexcitablebioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Junko KasuyaDepartment of Anesthesia, Carver College of Medicine, University of Iowa, 1-376 BSB, 51 Newton Road, Iowa City, IA 52242, United States. Electronic address: junko-kasuya@uiowa.edu.
Wayne JohnsonDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, United States; Interdisciplinary Graduate Program in Genetics, University of Iowa, IA 52242, United States. Electronic address: wayne-a-johnson@uiowa.edu.
Hung-Lin ChenInterdisciplinary Graduate Program in Genetics, University of Iowa, IA 52242, United States.
Toshihiro KitamotoInterdisciplinary Graduate Program in Genetics, University of Iowa, IA 52242, United States. Electronic address: toshi-kitamoto@uiowa.edu.
University of Iowa · US

Funding

Roles of hemocytes and bioactive lipids in the modulation of neuronal excitability and seizure behavior in Drosophila voltage-gated sodium channel mutantsR21NS127364 · NINDS · UNIVERSITY OF IOWA · PI KITAMOTO, TOSHIHIRO · 2022 to 2023
$425k
Modulation of neurological phenotypes by the gut microbiota in DrosophilaR21NS101545 · NINDS · UNIVERSITY OF IOWA · PI KITAMOTO, TOSHIHIRO · 2017 to 2018
$419k
Genetic suppression of seizure-like phenotypes in a Drosophila model of epilepsyR03NS101541 · NINDS · UNIVERSITY OF IOWA · PI KITAMOTO, TOSHIHIRO · 2017 to 2018
$153k
NINDS NIH HHS R03 NS101541NINDS NIH HHS R21 NS101545NINDS NIH HHS R21 NS127364
6 · The paper itself

Abstract

Dietary modifications often have a profound impact on the penetrance and expressivity of neurological phenotypes that are caused by genetic defects. Our previous studies in Drosophila melanogaster revealed that seizure-like phenotypes of gain-of-function voltage-gated sodium (Na

Indexed as

DrosophilaDrosophila ProteinsAnimalsDietary SupplementsDrosophila melanogasterLipidsMilkMutationPhenotypeSeizuresDrosophila ProteinsLipidsgene-environment interactionneuronal developmentRNA-sequencingseizurevoltage-gated sodium channelα-linolenic acid

Identifiers

PMID37004908
PMCPMC10200772
OpenAlexW4362471662

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.