Evidence map›Paper›PMID 37004723›Full record

ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2023

Contributions of mutation and selection to regulatory variation: lessons from the

Patricia J Wittkopp

Open access · bronzeAbstract readReview
In one paragraph

Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Interdisciplinary approaches to predicting evolutionary biology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 3 countries.

Patricia J WittkoppDepartment of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0001-7619-0048
University of Michigan · US

Funding

Genetic mechanisms and evolutionary processes underlying diversity within and between speciesR35GM118073 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WITTKOPP, PATRICIA JEAN · 2016 to 2025
$4.1M
Evolution of Gene Expression in YeastR01GM108826 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WITTKOPP, PATRICIA JEAN · 2013 to 2015
$865k
NIGMS NIH HHS R01 GM108826NIGMS NIH HHS R35 GM118073
6 · The paper itself

Abstract

Heritable variation in gene expression is common within and among species and contributes to phenotypic diversity. Mutations affecting either

Indexed as

Saccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsMutationPolymorphism, GeneticSelection, GeneticSaccharomyces cerevisiae Proteinscis-regulatoryfitnessgene-by-environmentpleiotropyregulatory networktrans-regulatory

Identifiers

PMID37004723
PMCPMC10067266
OpenAlexW4362508862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.