Evidence map›Paper›PMID 37004688›Full record

ArticleObesity surgery2023

Application of Scores Assessing Histological Activity and Estimated Long-Term Risk Analysis of Hepatic Decompensation of Non-Alcoholic Fatty Liver Disease in Individuals Undergoing Bariatric Surgery.

Marcelo Hatto, Victor Kenzo Ivano, Martinho Antonio Gestic, Murillo Pimentel Utrini, Felipe David Mendonça Chaim, Francisco Callejas-Neto, Elinton Adami Chaim, Everton Cazzo

Abstract read
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Article in Obesity surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marcelo HattoDepatment of Surgery, School of Medical Sciences, State University of Campinas (UNICAMP), Sao Paulo, Campinas, Brazil.
Victor Kenzo IvanoDepatment of Surgery, School of Medical Sciences, State University of Campinas (UNICAMP), Sao Paulo, Campinas, Brazil.
Martinho Antonio GesticDepatment of Surgery, School of Medical Sciences, State University of Campinas (UNICAMP), Sao Paulo, Campinas, Brazil.
Murillo Pimentel UtriniDepatment of Surgery, School of Medical Sciences, State University of Campinas (UNICAMP), Sao Paulo, Campinas, Brazil.
Felipe David Mendonça ChaimDepatment of Surgery, School of Medical Sciences, State University of Campinas (UNICAMP), Sao Paulo, Campinas, Brazil.
Francisco Callejas-NetoDepatment of Surgery, School of Medical Sciences, State University of Campinas (UNICAMP), Sao Paulo, Campinas, Brazil.
Elinton Adami ChaimDepatment of Surgery, School of Medical Sciences, State University of Campinas (UNICAMP), Sao Paulo, Campinas, Brazil.
Everton CazzoDepatment of Surgery, School of Medical Sciences, State University of Campinas (UNICAMP), Sao Paulo, Campinas, Brazil. notrevezzo@yahoo.com.br.ORCID http://orcid.org/0000-0002-5804-1580

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHistological scores can estimate disease staging, allowing a standardization of the assessment of non-alcoholic fatty liver disease (NAFLD). The prediction of risk of NAFLD progression is relevant to allow the planning of interventions.

objectiveTo analyze the application of the Iowa NAFLD decompensation risk score, the NAFLD activity score (NAS), and steatosis-activity-fibrosis score (SAF) and to assess correlations between these scores.

methodsThis is a retrospective cross-sectional study enrolling 76 individuals who underwent bariatric surgery at a tertiary university hospital. Liver biopsy was performed during procedures; histological scores were then assessed. The Iowa score was calculated using age, diabetes, and platelet count.

results89.5% were female and mean age was 39.1 ± 9.6 years. Mean BMI was 38.2 ± 3.7 kg/m

conclusionThe Iowa score demonstrated that individuals with obesity present with a significant long-term risk of NAFLD-related events. There were high rates of moderate/severe forms of NAFLD assessed by NAS and SAF scores. There were no significant correlations between Iowa and NAS/SAF scores.

Indexed as

Bariatric SurgeryNon-alcoholic Fatty Liver DiseaseObesity, MorbidAdultBiopsyCross-Sectional StudiesFemaleFibrosisHumansLiverMaleMiddle AgedRetrospective StudiesRisk AssessmentBariatric SurgeryLiver function testsNon-alcoholic fatty liver diseaseObesitySteatohepatitis

Identifiers

PMID37004688

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.