ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2023
Trajectories of health-related quality of life and their predictors in adult COVID-19 survivors: A longitudinal analysis of the Biobanque Québécoise de la COVID-19 (BQC-19).
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 15 citations in OpenAlex.
- Health-related quality of life profiles and trajectories of patients with post COVID-19 condition: a latent Markov model.Archives of public health = Archives belges de sante publique · 2026Article
- Cell death-induced release of the pro-aging protein acyl CoA binding protein (ACBP) into the circulation.Cell death and differentiation · 2026Article
- Distinct plasma proteome signature at 3 months post-COVID-19 infection irrespective of post-COVID condition.Scientific reports · 2026Article
- The impact of testing positive versus negative for COVID-19 on health-related quality of life: cross-sectional evidence from the Alberta post-COVID-19 follow-up survey.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Validity of EQ-5D-5L breathing and cognition bolt-ons in non-hospitalized patients after COVID-19.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Post-COVID-19 social determinants of health and quality of life: a longitudinal study.Revista da Escola de Enfermagem da U S P · 2026Article
- Long COVID trajectories in the prospectively followed RECOVER-Adult US cohort.Nature communications · 2025Article
- Health-related quality of life of adult post COVID-19 condition patients three years after infection and patient characteristics associated with change over time: a longitudinal analysis from the CORFU study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Neurologic Manifestations of Long COVID Disproportionately Affect Young and Middle-Age Adults.Annals of neurology · 2025Article
- One-year trajectories of physical and mental health-related quality of life, fatigue and dyspnoea in COVID-19 survivors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Longitudinal study on health-related quality of life and multimorbidity: from trajectories to outcomes in China.Frontiers in public health · 2025Article
- Examining the Trajectory of Health-Related Quality of Life among Coronavirus Disease Patients.Journal of general internal medicine · 2024Article
- Health-Related Quality of Life for Patients with Post-Acute COVID-19 Syndrome: Identification of Symptom Clusters and Predictors of Long-Term Outcomes.Journal of general internal medicine · 2024Observational
- Longitudinal Changes in Physical Function and Their Impact on Health Outcomes in COVID-19 Patients.Nutrients · 2023Article
- Impact of COVID-19 Infection on Health-Related Quality of Life, Work Productivity and Activity Impairment by Symptom-Based Long COVID Status and Age in the US.Healthcare (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeA significant number of people will experience prolonged symptoms after COVID-19 infection that will greatly impact functional capacity and quality of life. The aim of this study was to identify trajectories of health-related quality of life (HRQOL) and their predictors among adults diagnosed with COVID-19.
methodsThis is a retrospective analysis of an ongoing prospective cohort study (BQC-19) including adults (≥18y) recruited from April 2020 to March 2022. Our primary outcome is HRQOL using the EQ-5D-5L scale. Sociodemographic, acute disease severity, vaccination status, fatigue, and functional status at onset of the disease were considered as potential predictors. The latent class mixed model was used to identify the trajectories over an 18-month period in the cohort as a whole, as well as in the inpatient and outpatient subgroups. Multivariable and univariable regressions models were undertaken to detect predictors of decline.
results2163 participants were included. Thirteen percent of the outpatient subgroup (2 classes) and 28% in the inpatient subgroup (3 classes) experienced a more significant decline in HRQOL over time than the rest of the participants. Among all patients, age, sex, disease severity and fatigue, measured on the first assessment visit or on the first day after hospital admission (multivariable models), were identified as the most important predictors of HRQOL decline. Each unit increase in the SARC-F and CFS scores increase the likelihood of belonging to the declining trajectory (univariable models).
conclusionAlthough to different degrees, similar factors explain the decline in HRQOL over time among the overall population, people who have been hospitalized or not. Clinical functional capacity scales could help to determine the risk of HRQOL decline.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.