Evidence map›Paper›PMID 37004601›Full record

ReviewVirus genes2023

Characterization of Phietavirus Henu 2 in the virome of individuals with acute gastroenteritis.

Endrya do Socorro Fôro Ramos, Santana Lobato Bahia, Geovani de Oliveira Ribeiro, Fabiola Villanova, Flávio Augusto de Pádua Milagres, Rafael Brustulin, Ramendra Pati Pandey, Xutao Deng, Eric Delwart, Antonio Charlys da Costa and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Virus genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

Endrya do Socorro Fôro RamosLaboratório de Diversidade Viral, Instituto de Ciências Biológicais, Universidade Federal do Pará, Belém, Pará, 66075-000, Brazil.
Santana Lobato BahiaLaboratório de Diversidade Viral, Instituto de Ciências Biológicais, Universidade Federal do Pará, Belém, Pará, 66075-000, Brazil.
Geovani de Oliveira RibeiroLaboratório de Diversidade Viral, Instituto de Ciências Biológicais, Universidade Federal do Pará, Belém, Pará, 66075-000, Brazil.
Fabiola VillanovaLaboratório de Diversidade Viral, Instituto de Ciências Biológicais, Universidade Federal do Pará, Belém, Pará, 66075-000, Brazil.
Flávio Augusto de Pádua MilagresSecretaria de Saúde do Tocantins, Palmas, Tocantins, 77453-000, Brazil.
Rafael BrustulinSecretaria de Saúde do Tocantins, Palmas, Tocantins, 77453-000, Brazil.
Ramendra Pati PandeyCentre for Drug Design Discovery and Development (C4D), SRM University Delhi-NCR, Rajiv Gandhi Education City, Sonepat, Haryana, 131029, India.
Xutao DengVitalant Research Institute, 270 Masonic Avenue, San Francisco, CA, 94118-4417, USA.
Eric DelwartVitalant Research Institute, 270 Masonic Avenue, San Francisco, CA, 94118-4417, USA.
Antonio Charlys da CostaInstituto de Medicina Tropical, Universidade de São Paulo, São Paulo, 05403-000, Brazil. charlysbr@yahoo.com.br.
Élcio LealLaboratório de Diversidade Viral, Instituto de Ciências Biológicais, Universidade Federal do Pará, Belém, Pará, 66075-000, Brazil. elcioleal@gmail.com.
Universidade Federal do Pará · BRUniversidade do Tocantins · BRInstituto de Medicina Avançada · BRPacific Research Institute · USSRM University · INUniversity of California, San Francisco · US

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 302677/2019-4
6 · The paper itself

Abstract

There is a growing interest in phages as potential biotechnological tools in human health owing to the antibacterial activity of these viruses. In this study, we characterized a new member (named PhiV_005_BRA/2016) of the recently identified phage species Phietavirus Henu 2. PhiV_005_BRA/2016 was detected through metagenomic analysis of stool samples of individuals with acute gastroenteritis. PhiV_005_BRA/2016 contains double-stranded linear DNA (dsDNA), it has a genome of 43,513 base pairs (bp), with a high identity score (99%) with phage of the genus Phietavirus, species of Phietavirus Henu 2. Life style prediction indicated that PhiV_005_BRA/2016 is a lysogenic phage whose the main host is methicillin-resistant Staphylococcus aureus (MRSA). Indeed, we found PhiV_005_BRA/2016 partially integrated in the genome of distinct MRSA strains. Our findings highlights the importance of large-scale screening of bacteriophages to better understand the emergence of multi-drug resistant bacterial.

Indexed as

BacteriophagesGastroenteritisMethicillin-Resistant Staphylococcus aureusSiphoviridaeStaphylococcal InfectionsHumansViromeBiotechnologyGastroenteritisMethicillin-resistantPhagePhietavirusStaphylococcus aureus

Identifiers

PMID37004601
OpenAlexW4362506736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.