ArticleJournal of neurology2023
Long-term outcome after decompressive hemicraniectomy for malignant middle cerebral artery infarction.
Article in Journal of neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Decompressive hemicraniectomy as a salvage therapy in the Neuro-ICU: a meta-analysis of neurologic outcomes for malignant middle cerebral artery infarction.Frontiers in medicine · 2026Pooled it
- Decompressive Craniectomy in Ischemic Stroke: Neurosurgical Perspectives on Patient Outcomes and Psychological Impact on Family.Asian journal of neurosurgery · 2026Article
- Full Medical Support versus Limited Medical Care in Malignant Middle Cerebral Artery Infarction after Successful Recanalization for Large-Vessel Occlusion Stroke.Neurocritical care · 2026Article
- Long-term functional outcomes and caregiver burden in survivors after decompressive hemicraniectomy for malignant hemispheric infarction: a real-world experience from South India.BMJ neurology open · 2026Article
- [Focus on neurological intensive care medicine 2022/2023 : Summary of selected intensive medical care studies].Die Anaesthesiologie · 2023Article
- Long-term quality of life after decompressive craniectomy.Frontiers in neurology · 2023Article
Corrections and comments
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough decompressive hemicraniectomy (DHC) is a lifesaving treatment strategy for patients with malignant middle cerebral artery infarction (mMCAi), only one in four patients achieves low to moderate post-stroke disability according to previous studies. However, the short follow-up periods in prior studies could have overestimated the poor clinical prognosis. This study therefore examined the long-term outcome after DHC for mMCAi.
methodsWe retrospectively included all patients who had undergone DHC after mMCAi at the University Hospital Graz between 2006 and 2019. Demographics, clinical data and complications were collected from electronic clinical patient records. To investigate long-term prognosis, all patients were followed up to 14 years after stroke including quality of life (QOL) assessment. Post-stroke disability was rated according to the modified Rankin Scale (mRS).
resultsOf 47 patients that had undergone DHC for mMCAi, follow-up data were available in 40 patients (mean age: 48 years; 40% female). Six months after the mMCAi, 14 patients had died (35%) and nine (23%) had a low to moderate post-stroke disability (mRS 0-3). Of 26 stroke survivors, half (50%) showed further mRS improvement (≥ 1 point) during the long-term follow-up period (mean follow-up time: 8 years). At last follow-up, 17 patients had achieved an mRS score of ≤ 3 (65% versus 35% after 6 months; p = 0.008) and 55% had no signs of depression and anxiety, and 50% no signs of pain or discomfort in QOL assessment.
conclusionThis study shows substantial long-term improvement of functional disability and reasonable QOL in mMCAi patients after DHC.
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