Evidence map›Paper›PMID 37004301›Full record

ArticleJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2023

Influence of mild cognitive impairment on patient and care partner decision-making for acute ischemic stroke.

Emilie M Blair, Bailey K Reale, Darin B Zahuranec, Jane Forman, Kenneth M Langa, Bruno J Giordani, Brenda L Plassman, Kathleen A Welsh-Bohmer, Jing Wang, Colleen D Kollman and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Emilie M BlairDepartment of Internal Medicine and Cognitive Health Services Research Program, U-M Medical School, Ann Arbor, MI, USA.
Bailey K RealeDepartment of Internal Medicine and Cognitive Health Services Research Program, U-M Medical School, Ann Arbor, MI, USA; Lake Erie College of Osteopathic Medicine at Seton Hill, LECOM, Greensburg, PA, USA.
Darin B ZahuranecDepartment of Neurology and Stroke Program, U-M, Ann Arbor, MI, USA.
Jane FormanDepartment of Internal Medicine and Cognitive Health Services Research Program, U-M Medical School, Ann Arbor, MI, USA; VA Ann Arbor Healthcare System, Ann Arbor, MI, USA; Institute for Social Research, U-M, Ann Arbor, MI, USA.
Kenneth M LangaDepartment of Internal Medicine and Cognitive Health Services Research Program, U-M Medical School, Ann Arbor, MI, USA; Institute for Healthcare Policy and Innovation, U-M, Ann Arbor, MI, USA; VA Ann Arbor Healthcare System, Ann Arbor, MI, USA; Institute for Social Research, U-M, Ann Arbor, MI, USA.
Bruno J GiordaniDepartment of Psychiatry and Michigan Alzheimer's Disease Center, U-M, Ann Arbor, MI, USA.
Brenda L PlassmanDepartment of Psychiatry and Behavioral Science, Duke University School of Medicine, Durham, NC, USA.
Kathleen A Welsh-BohmerDepartment of Psychiatry and Behavioral Science, Duke University School of Medicine, Durham, NC, USA.
Jing WangDepartment of Psychiatry and Behavioral Science, Duke University School of Medicine, Durham, NC, USA.
Colleen D KollmanKollman Research Services, Ann Arbor, MI, USA.
Deborah A LevineDepartment of Internal Medicine and Cognitive Health Services Research Program, U-M Medical School, Ann Arbor, MI, USA; Department of Neurology and Stroke Program, U-M, Ann Arbor, MI, USA; VA Ann Arbor Healthcare System, Ann Arbor, MI, USA. Electronic address: deblevin@umich.edu.
Duke University · USUniversity of Michigan · USVA Ann Arbor Healthcare System · USLake Erie College of Osteopathic Medicine · US

Funding

Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
Michigan Alzheimer's Disease Core CenterP30AG053760 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALBIN, ROGER L · 2016 to 2020
$10.1M
The Effect of Lower Blood Pressure over the Life Course on Late-life Cognition in Blacks, Hispanics, and Whites (BP-COG)R01NS102715 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEVINE, DEBORAH ALLISON · 2017 to 2021
$3.8M
Decision Making for Cardiovascular Therapy in Adults with Mild Cognitive ImpairmentR01AG051827 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEVINE, DEBORAH ALLISON · 2016 to 2020
$3.6M
The Effect of Vascular Risk Factors on Risk of Alzheimer's Disease and Related Dementias after Stroke (STROKE COG)RF1AG068410 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEVINE, DEBORAH ALLISON · 2020 to 2020
$3.1M
NIA NIH HHS P30 AG024824NIA NIH HHS P30 AG053760NIA NIH HHS R01 AG051827NIA NIH HHS RF1 AG068410NINDS NIH HHS R01 NS102715
6 · The paper itself

Abstract

goalsEvidence suggests that patients with mild cognitive impairment (MCI) receive fewer treatments for acute ischemic stroke and other cardiovascular diseases than patients with normal cognition. Little is known about how patient and care partner preferences for ischemic stroke treatment differ between the patient population with MCI and the population with normal cognition. This study aimed to understand how patient MCI diagnosis influences patient and care partner decision-making for acute ischemic stroke treatments.

methodsMulti-center qualitative study using in-person semi-structured interviews with 20 MCI and normal cognition patient-care partner dyads using a standard guide. The present study reports results on patient and care partner preferences for a clinical vignette patient to receive three non-invasive treatments (intravenous tissue plasminogen activator, inpatient rehabilitation, and secondary preventive medications) and two invasive treatments (feeding tube and carotid endarterectomy) after acute ischemic stroke. We used qualitative content analysis to identify themes.

findingsWe identified three major themes: (1) Patients with MCI desired non-invasive treatments after stroke, similar to patients with normal cognition and for similar reasons; (2) Patients with MCI expressed different preferences than patients with normal cognition for two invasive treatments after stroke: carotid endarterectomy and feeding tube placement; and (3) Patients with MCI expressed more skepticism of the stroke treatment options and less decisiveness in decision-making than patients with normal cognition.

conclusionsThese results suggest that patient MCI diagnosis may contribute to differences in patient and care partner preferences for invasive treatments after stroke, but not for non-invasive treatments.

Indexed as

Cognitive DysfunctionIschemic StrokeStrokeCaregiversHumansTissue Plasminogen ActivatorTissue Plasminogen ActivatorAgingDecision-makingMild cognitive impairmentTreatment

Identifiers

PMID37004301
PMCPMC10499500
OpenAlexW4362467807

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.