Evidence map›Paper›PMID 37004166›Full record

ArticleRheumatology (Oxford, England)2023

Paediatric rheumatologists do not score the physician's global assessment of juvenile idiopathic arthritis disease activity in the same way.

Maria Backström, Maarit Tarkiainen, Beth S Gottlieb, Chiara Trincianti, Tingting Qiu, Esi Morgan, Daniel J Lovell, Francesca Bovis, Eliisa Löyttyniemi, Nicolino Ruperto and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Rheumatology (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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  8. Sonographic and Disease Activity Findings Related With Medication Change in JIA: A Historical Cohort Study.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 3 countries.

Maria BackströmDepartment of Pediatrics, The Wellbeing Services County of Ostrobothnia, Vaasa, Finland.ORCID 0000-0002-8632-8634
Maarit TarkiainenPediatric Research Center, Helsinki University Hospital and University of Helsinki, New Children's Hospital, Helsinki, Finland.
Beth S GottliebPediatric Rheumatology, Cohen Children's Medical Center, Zucker School of Medicine at Hofstra/Northwell, New York, USA.
Chiara TrinciantiDepartment of Health Sciences, University of Genoa, Genoa, Italy.
Tingting QiuDepartment of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, OH, USA.
Esi MorganDepartment of Pediatrics, University of Washington School of Medicine, Seattle Children's Hospital, Seattle, WA, USA.
Daniel J LovellDivision of Rheumatology, Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine, OH, USA.ORCID 0000-0003-1604-0130
Francesca BovisDepartment of Health Sciences, University of Genoa, Genoa, Italy.
Eliisa LöyttyniemiDepartment of Biostatistics, University of Turku, Turku, Finland.
Nicolino RupertoPediatria II-PRINTO, Istituto Giannina Gaslini Istituto Pediatrico di Ricovero e Cura a Carattere Scientifico, Genova, Italy.ORCID 0000-0001-8407-7782
Paula VähäsaloPEDEGO Research Unit, University of Oulu, Oulu, Finland.
Alessandro ConsolaroDepartment of Health Sciences, University of Genoa, Genoa, Italy.
Cincinnati Children's Hospital Medical Center · USIstituto Giannina Gaslini · ITUniversity of Genoa · ITCohen Children's Medical Center · USOulu University Hospital · FISeattle Children's Hospital · USUniversity of Helsinki · FIUniversity of Oulu · FIUniversity of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the heterogeneity in factors affecting physician's global assessment of disease activity (PhGA) and in PhGA scoring of multiple JIA patient's case scenarios.

methodsAn electronic web-based questionnaire of factors potentially considered in PhGA was sent worldwide to members of PRINTO and the Pediatric Rheumatology Care and Outcomes Improvement Network (PR-COIN). The respondents were asked to rate from 0 to 100 the relevance of 17 factors possibly affecting PhGA scoring and to derive a PhGA score of 17 detailed JIA patient cases. The median and interquartile range was used to measure the heterogeneity in the scoring. To demonstrate the consistency among the PhGA scores of the patient cases provided by multiple physicians, we assessed the inter-rater reliability using intra-class correlation.

resultsThe questionnaire was completed by 491 respondents. A large individual variation was observed in the impact of different factors on PhGA when assessing JIA. For non-systemic JIA the presence of fever had the largest variation and swollen joint count had the smallest. For sJIA, the largest variation was seen in the presence of erosions and the smallest in the presence of fever. The intra-class correlation of the group for PhGA scoring of patient cases was 0.53 (95% CI 0.38, 0.72).

conclusionsIn a sample of worldwide respondents, the scoring of the PhGA is divergent. Consensus on PhGA scoring guidelines is required to obtain a consistent assessment of patients.

Indexed as

Arthritis, JuvenilePhysiciansChildHumansReproducibility of ResultsRheumatologistsSurveys and Questionnairesdisease activityJIAoutcome measurephysician’s global assessment

Identifiers

PMID37004166
PMCPMC10547524
OpenAlexW4362458575

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.