Evidence map›Paper›PMID 37004111›Full record

Trial reportJournal of neuroengineering and rehabilitation2023

Immediate improvements in post-stroke gait biomechanics are induced with both real-time limb position and propulsive force biofeedback.

Vincent Santucci, Zahin Alam, Justin Liu, Jacob Spencer, Alec Faust, Aijalon Cobb, Joshua Konantz, Steven Eicholtz, Steven Wolf, Trisha M Kesar

Registry-linked trialOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in Journal of neuroengineering and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03466372 (Innovative Biofeedback Strategies for Gait Training), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03466372 nacompletednot on this map

Innovative Biofeedback Strategies for Gait Training

TypeinterventionalSponsorEmory UniversityRan2018 to 2018Enrolled20ConditionsStroke, Cardiovascular, Gait, HemiplegicArmsbiofeedback
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Effects of Belt Accelerations During Push-Off on Propulsion Mechanics in Individuals Post-Stroke.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Vincent SantucciDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, GA, USA.
Zahin AlamDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, GA, USA.
Justin LiuDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, GA, USA.
Jacob SpencerDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, GA, USA.
Alec FaustDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, GA, USA.
Aijalon CobbDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, GA, USA.
Joshua KonantzDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, GA, USA.
Steven EicholtzDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, GA, USA.
Steven WolfDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, GA, USA.
Trisha M KesarDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, GA, USA. tkesar@emory.edu.
Emory University · USEmory Rehabilitation Hospital · US

Funding

Biomechanical and neural mechanisms of post-stroke gait trainingR01HD095975 · NICHD · EMORY UNIVERSITY · PI KESAR, TRISHA · 2019 to 2024
$2.9M
Innovative Biofeedback Interface for Enhancing Stroke Gait RehabilitationR21HD095138 · NICHD · EMORY UNIVERSITY · PI KESAR, TRISHA · 2018 to 2019
$427k
NICHD NIH HHS R01 HD095975NICHD NIH HHS R21 HD095138
6 · The paper itself

Abstract

backgroundParetic propulsion [measured as anteriorly-directed ground reaction forces (AGRF)] and trailing limb angle (TLA) show robust inter-relationships, and represent two key modifiable post-stroke gait variables that have biomechanical and clinical relevance. Our recent work demonstrated that real-time biofeedback is a feasible paradigm for modulating AGRF and TLA in able-bodied participants. However, the effects of TLA biofeedback on gait biomechanics of post-stroke individuals are poorly understood. Thus, our objective was to investigate the effects of unilateral, real-time, audiovisual TLA versus AGRF biofeedback on gait biomechanics in post-stroke individuals.

methodsNine post-stroke individuals (6 males, age 63 ± 9.8 years, 44.9 months post-stroke) participated in a single session of gait analysis comprised of three types of walking trials: no biofeedback, AGRF biofeedback, and TLA biofeedback. Biofeedback unilaterally targeted deficits on the paretic limb. Dependent variables included peak AGRF, TLA, and ankle plantarflexor moment. One-way repeated measures ANOVA with Bonferroni-corrected post-hoc comparisons were conducted to detect the effect of biofeedback on gait biomechanics variables.

resultsCompared to no-biofeedback, both AGRF and TLA biofeedback induced unilateral increases in paretic AGRF. TLA biofeedback induced significantly larger increases in paretic TLA than AGRF biofeedback. AGRF biofeedback increased ankle moment, and both feedback conditions increased non-paretic step length. Both types of biofeedback specifically targeted the paretic limb without inducing changes in the non-paretic limb.

conclusionsBy showing comparable increases in paretic limb gait biomechanics in response to both TLA and AGRF biofeedback, our novel findings provide the rationale and feasibility of paretic TLA as a gait biofeedback target for post-stroke individuals. Additionally, our results provide preliminary insights into divergent biomechanical mechanisms underlying improvements in post-stroke gait induced by these two biofeedback targets. We lay the groundwork for future investigations incorporating greater dosages and longer-term therapeutic effects of TLA biofeedback as a stroke gait rehabilitation strategy. Trial registration NCT03466372.

Indexed as

StrokeStroke RehabilitationAgedBiomechanical PhenomenaGaitHumansMaleMiddle AgedWalkingFeedbackPushoffStroke gait rehabilitationTrailing limb angle

Identifiers

PMID37004111
PMCPMC10064559
OpenAlexW4362522352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.