Evidence map›Paper›PMID 37003970›Full record

ArticleBMC infectious diseases2023

The impact of ethnic background on ICU care and outcome in sepsis and septic shock - A retrospective multicenter analysis on 17,949 patients.

Andreas Koköfer, Behrooz Mamandipoor, Maria Flamm, Richard Rezar, Sarah Wernly, Christian Datz, Christian Jung, Venet Osmani, Bernhard Wernly, Raphael Romano Bruno

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Andreas KoköferDepartment of Anaesthesiology, Perioperative Medicine and Intensive Care Medicine, Paracelsus Medical University of Salzburg, Salzburg, Austria.
Behrooz MamandipoorFondazione Bruno Kessler Research Institute, Trento, Italy.
Maria FlammInstitute of General Practice, Family Medicine and Preventive Medicine, Paracelsus Medical University of Salzburg, Salzburg, Austria.
Richard RezarDepartment of Cardiology, Paracelsus Medical University of Salzburg, Salzburg, Austria.
Sarah WernlyDepartment of Internal Medicine, General Hospital Oberndorf, Teaching Hospital, Paracelsus Medical University of Salzburg, Oberndorf, Austria.
Christian DatzDepartment of Internal Medicine, General Hospital Oberndorf, Teaching Hospital, Paracelsus Medical University of Salzburg, Oberndorf, Austria.
Christian JungDivision of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Venet OsmaniFondazione Bruno Kessler Research Institute, Trento, Italy.
Bernhard Wernly *Institute of General Practice, Family Medicine and Preventive Medicine, Paracelsus Medical University of Salzburg, Salzburg, Austria. bernhard@wernly.net.
Raphael Romano Bruno *Division of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany. Raphael.bruno@med.uni-duesseldorf.de.ORCID http://orcid.org/0000-0003-3776-3530
University of Salzburg · ATDüsseldorf University Hospital · DEFondazione Bruno Kessler · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have been inconclusive about racial disparities in sepsis. This study evaluated the impact of ethnic background on management and outcome in sepsis and septic shock.

methodsThis analysis included 17,146 patients suffering from sepsis and septic shock from the multicenter eICU Collaborative Research Database. Generalized estimated equation (GEE) population-averaged models were used to fit three sequential regression models for the binary primary outcome of hospital mortality.

resultsNon-Hispanic whites were the predominant group (n = 14,124), followed by African Americans (n = 1,852), Hispanics (n = 717), Asian Americans (n = 280), Native Americans (n = 146) and others (n = 830). Overall, the intensive care treatment and hospital mortality were similar between all ethnic groups. This finding was concordant in patients with septic shock and persisted after adjusting for patient-level variables (age, sex, mechanical ventilation, vasopressor use and comorbidities) and hospital variables (teaching hospital status, number of beds in the hospital).

conclusionWe could not detect ethnic disparities in the management and outcomes of critically ill septic patients and patients suffering from septic shock. Disparate outcomes among critically ill septic patients of different ethnicities are a public health, rather than a critical care challenge.

Indexed as

SepsisShock, SepticCritical IllnessEthnicityHospital MortalityHospitals, TeachingHumansIntensive Care UnitsRetrospective StudiesCritically illElderlyGeriatricIntensive careOctogenarianOldSepsisVery elderlyVery old

Identifiers

PMID37003970
PMCPMC10064763
OpenAlexW4362523278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.