Evidence map›Paper›PMID 37003532›Full record

ArticleJournal of advanced research2024

Targeted m

Xiaoling Ying, Yapeng Huang, Bixia Liu, WenYu Hu, Ding Ji, Cong Chen, Haiqing Zhang, Yaomin Liang, Yifan Lv, Weidong Ji

Open access · goldAbstract read
In one paragraph

Article in Journal of advanced research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. The Role of NMedComm · 2026
    Review
  4. Article
  5. Targeting mDiscover oncology · 2026
    Review
  6. RNA mCell biology and toxicology · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Unraveling the dual role of METTL3-mediated mCancer biology & therapy · 2025
    Review
  11. mMolecules (Basel, Switzerland) · 2025
    Review
  12. Article
  13. Exploring the methyl-verse: Dynamic interplay of epigenome and m6A epitranscriptome.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  14. Review
  15. Review
  16. Article
  17. Epitranscriptomic RNA mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  18. mCell biology and toxicology · 2024
    Article
  19. YTHDF1 in Tumor Cell Metabolism: An Updated Review.Molecules (Basel, Switzerland) · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Xiaoling YingCenter for Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China; Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Yapeng HuangCenter for Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Bixia LiuCenter for Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
WenYu HuCenter for Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Ding JiDepartment of Otolaryngology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Cong ChenCenter for Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Haiqing ZhangCenter for Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Yaomin LiangCenter for Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Yifan LvDepartment of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University, Guangdong Key Laboratory of Urology, Guangzhou 510230, China.
Weidong JiCenter for Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China. Electronic address: jiweidong@mail.sysu.edu.cn.
Sun Yat-sen University · CNFirst Affiliated Hospital of Guangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionN6-methyladenosine (m

objectivesWe aim to develop a multisite dCasRx- m

methodsThe multisite dCasRx- m

resultsWe designed a targeted ITGA6 multi-locus guide (g)RNA and established a bidirectional deactivated RfxCas13d (dCasRx)-based m

conclusionOur study proposes a novel therapeutic tool for the treatment of BC by applying the multisite dCasRx-m

Indexed as

RNA, Guide, CRISPR-Cas SystemsUrinary Bladder NeoplasmsAnimalsCell Line, TumorDemethylationHumansIntegrin alpha6MethyltransferasesMiceMice, NudeRNA, MessengerIntegrin alpha6ITGA6 protein, humanMethyltransferasesMETTL3 protein, humanRNA, Guide, CRISPR-Cas SystemsRNA, MessengerAdeno-associated viralBladder cancerdCasRxITGA6MultisiteN(6)-methyladenosine

Identifiers

PMID37003532
PMCPMC10834799
OpenAlexW4361280293

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.