SynthesisJournal of pain and symptom management2023
Psychiatric Comorbidities and Outcomes in Palliative and End-of-Life Care: A Systematic Review.
Synthesis in Journal of pain and symptom management, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Trial
- Top Ten Tips Palliative Care Clinicians Should Know About Total Pain.Journal of palliative medicine · 2026Article
- Are there inequities in the assessment or management of pain for people with severe mental illness living with life-threatening diseases? A mixed-methods systematic review.Palliative care and social practice · 2026Review
- Prevalence and comorbidity of mental health concerns, alcohol and drug use among young women in the urban slums of Kampala, Uganda: findings from the TOPOWA study.BMC public health · 2025Article
- Staff-Identified Palliative Care Needs Among Programs of All-Inclusive Care for the Elderly (PACE): A Survey Study.Journal of the American Medical Directors Association · 2025Article
- Home-based psilocybin-assisted therapy for a patient with advanced cancer: A case report.Palliative & supportive care · 2025Article
- Ecological Momentary Assessment in Palliative Care: A Qualitative Study of Patient and Clinician Perspectives.The American journal of hospice & palliative care · 2025Article
- Primary Mental Health Competencies for Hospice and Palliative Medicine Physicians: A Delphi Study.Journal of pain and symptom management · 2025Article
- Use of brief, simple anxiety assessment tools in palliative care - yes, we can: a cross-sectional observational study of anxiety visual analog scale and numeric rating scale.BMC palliative care · 2025Observational
- Mind the Gap: Understanding Palliative Care Clinician Attitudes Toward Mental Health Training.The American journal of hospice & palliative care · 2025Article
- High Frequency of Depression in Advanced Cancer with Concomitant Comorbidities: A Registry Study.Cancers · 2025Article
- Top Ten Tips Palliative Care Clinicians Should Know About the Psychiatric Manifestations of Nonpsychiatric Serious Illness and Treatments.Journal of palliative medicine · 2024Article
- Top Ten Tips Palliative Care Clinicians Should Know About the Physical Manifestations of Psychiatric Illness and Treatment.Journal of palliative medicine · 2024Article
- Interventions for behavioral health comorbidities in the hospice setting: a scoping review.Annals of palliative medicine · 2024Article
- Palliative Care Psychiatry: Building Synergy Across the Spectrum.Current psychiatry reports · 2024Review
- Mental Health Integration and Delivery in the Hospice and Palliative Medicine Setting: A National Survey of Clinicians.Journal of pain and symptom management · 2024Article
- Hospice and Palliative Medicine Fellowship Training in Mental Health: A Survey of Program Directors.Journal of pain and symptom management · 2023Article
- A Point Prevalence Study of the Provision of Palliative Care for Adult Inpatients With Mental Health Issues.Journal of the American Psychiatric Nurses AssociationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundAlthough psychiatric comorbidities are common among individuals at end of life, their impact on outcomes is poorly understood.
methodsWe conducted a systematic literature review of six databases following preferred reporting items for systematic reviews and meta-analyses guidelines and aimed at assessing the relationship between psychiatric comorbidities and outcomes in palliative and end-of-life care. Six databases were included in our search. This review is registered on PROSPERO (CRD42022335922).
resultsOur search generated 7472 unique records. Eighty-eight full texts were reviewed for eligibility and 43 studies were included in the review. Clinically, psychiatric comorbidity was associated with poor quality of life, increased physical symptom burden, and low function. The impact of psychiatric comorbidity on health utilization varied, though many studies suggested that psychiatric comorbidity increased utilization of palliative care services. Quality of evidence was limited by lack of consistent approach to confounding variables as well as heterogeneity of the included studies.
conclusionPsychiatric comorbidity is associated with significant differences in care utilization and clinical outcome among patients at end of life. In particular, patients with psychiatric comorbidity and serious illness are at high risk of poor quality of life and high symptom burden. Our finding that psychiatric comorbidity is associated with increased utilization of palliative care likely reflects the complexity and clinical needs of patients with serious illness and mental health needs. These data suggest that greater integration of mental health and palliative care services may enhance quality-of-life among patients at end of life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.