Evidence map›Paper›PMID 37002475›Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2023

Yoga Programme for Type 2 Diabetes Prevention (YOGA-DP) Among High-Risk People in India: A Multicenter Feasibility Randomized Controlled Trial.

Kaushik Chattopadhyay, Pallavi Mishra, Kavita Singh, Kalpana Singh, Tess Harris, Mark Hamer, Sheila Margaret Greenfield, Nandi Krishnamurthy Manjunath, Rukamani Nair, Somnath Mukherjee and 5 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 2 countries.

Kaushik ChattopadhyayLifespan and Population Health Academic Unit, University of Nottingham, Nottingham, UK. kaushik.chattopadhyay@nottingham.ac.uk.ORCID http://orcid.org/0000-0002-3235-8168
Pallavi MishraCentre for Chronic Disease Control, New Delhi, India.
Kavita SinghCentre for Chronic Disease Control, New Delhi, India.
Kalpana SinghCentre for Chronic Disease Control, New Delhi, India.
Tess HarrisPopulation Health Research Institute, St. George's University of London, London, UK.
Mark HamerDivision of Surgery and Interventional Science, Institute of Sport, Exercise and Health, University College London, London, UK.
Sheila Margaret GreenfieldInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.
Nandi Krishnamurthy ManjunathSwami Vivekananda Yoga Anusandhana Samsthana, Bengaluru, India.
Rukamani NairBapu Nature Cure Hospital and Yogashram, New Delhi, India.
Somnath MukherjeeBapu Nature Cure Hospital and Yogashram, New Delhi, India.
Nikhil TandonDepartment of Endocrinology, Metabolism and Diabetes, All India Institute of Medical Sciences, New Delhi, India.
Sarah Anne LewisLifespan and Population Health Academic Unit, University of Nottingham, Nottingham, UK.
Sanjay KinraDepartment of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Dorairaj PrabhakaranCentre for Chronic Disease Control, New Delhi, India.
YOGA-DP Study Team
Centre for Chronic Disease Control · INBapu Nature Cure Hospital & Yogashram · INUniversity of Nottingham · GBAll India Institute of Medical Sciences · INLondon School of Hygiene & Tropical Medicine · GBSt George's, University of London · GBSwami Vivekananda Yoga Anusandhana Samsthana · INUniversity College London · GBUniversity of Birmingham · GB

Funding

Medical Research Council MR/J000175/1Medical Research Council MR/R018278/1
6 · The paper itself

Abstract

introductionMany Indians are at high risk of type 2 diabetes mellitus (T2DM). The blood glucose level can be improved through a healthy lifestyle (such as physical activity and a healthy diet). Yoga can help in T2DM prevention, being a culturally appropriate approach to improving lifestyle. We developed the Yoga Programme for T2DM Prevention (YOGA-DP), a 24-week structured lifestyle education and exercise (Yoga) program that included 27 group Yoga sessions and self-practice of Yoga at home. In this study, the feasibility of undertaking a definitive randomized controlled trial (RCT) was explored that will evaluate the intervention's effectiveness among high-risk individuals in India.

methodsA multicenter, two-arm, parallel-group, feasibility RCT was conducted in India. The outcome assessors and data analysts were blinded. Adults with a fasting blood glucose level of 100-125 mg/dL (i.e., at high risk of T2DM) were eligible. Participants were randomized centrally using a computer-generated randomization schedule. In the intervention group, participants received YOGA-DP. In the control group, participants received enhanced standard care.

resultsIn this feasibility trial, the recruitment of participants took 4 months (from May to September 2019). We screened 711 people and assessed 160 for eligibility. Sixty-five participants (33 in the intervention group and 32 in the control group) were randomized, and 57 (88%) participants were followed up for 6 months (32 in the intervention group and 25 in the control group). In the intervention group, the group Yoga sessions were continuously attended by 32 (97%) participants (median (interquartile range, IQR) number of sessions attended = 27 (3)). In the intervention group, Yoga was self-practiced at home by 30 (91%) participants (median (IQR) number of days per week and minutes per day self-practiced = 2 (2) and 35 (15), respectively). In the control group, one (3%) participant attended external Yoga sessions (on Pranayama) for 1 week during the feasibility trial period. There was no serious adverse event.

conclusionsThe participant recruitment and follow-up and adherence to the intervention were promising in this feasibility study. In the control group, the potential contamination was low. Therefore, it should be feasible to undertake a definitive RCT in the future that will evaluate YOGA-DP's effectiveness among high-risk people in India. FEASIBILITY

trial registrationClinical Trials Registry-India (CTRI) CTRI/2019/05/018893; registered on May 1, 2019.

Indexed as

Blood glucoseDietFeasibility studyLifestylePhysical activityPrediabetesPreventionRandomized controlled trialYoga

Identifiers

PMID37002475
PMCPMC10066010
OpenAlexW4362467646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.