ArticleClinical oral investigations2023
Cerebral abscesses with odontogenic origin: a population-based cohort study.
Article in Clinical oral investigations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 17 citations in OpenAlex.
- Oral Diseases and Brain Pathologies: A Systematic Review with Narrative Synthesis of Clinical, Neuroimaging, and Mechanistic Evidence.Biomedicines · 2026Review
- Odontogenic Brain Abscess in a Hereditary Haemorrhagic Telangiectasia (HHT) Patient: Case Report with a Comprehensive Literature Review.Tropical medicine and infectious disease · 2026Article
- Brain abscess following right maxillary odontogenic infection in a patient with diabetes mellitus: a case report.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2025Article
- Brain Abscess From Dental Bacteria: A Case Report.Cureus · 2025Article
- Global trends in the microbial profile of odontogenic infections and its practical implications: A 70-year narrative review.Oral and maxillofacial surgery · 2025Review
- Article
- Results of bacterial cultivation are infrequently utilized in the treatment of patients hospitalized with severe odontogenic infections - a retrospective cohort study.Journal of oral microbiology · 2025Article
- Odontogenic brain abscess caused byJournal of oral microbiology · 2025Article
- Oral pathologic conditions and impaired cytokine response in patients with previous cerebral abscess or cervical necrotizing soft tissue infection.Frontiers in cellular and infection microbiology · 2025Observational
- Patients with severe odontogenic infections receive insufficient dental treatment before hospitalization - a retrospective cross-sectional study.Acta odontologica Scandinavica · 2024Article
- Augmented pathogen detection in brain abscess using metagenomic next-generation sequencing: a retrospective cohort study.Microbiology spectrum · 2024Article
- Undetected permanent dental inflammation as a possible trigger for brain abscesses? A retrospective analysis over the last 2 decades.Acta neurochirurgica · 2024Article
- A Report of Two Cases of Meningoencephalitis Caused byInfection and drug resistance · 2024Article
- Polymicrobial infections with specificJournal of oral microbiology · 2024Review
- Severe Infections after Tooth Removal: a Retrospective Cohort Study.Journal of oral & maxillofacial researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesRecent studies have indicated that cerebral abscess (CA) patients with odontogenic origin are on the rise. However, CA patients are often poorly characterized and with an unknown etiologic background. The purpose of this study is to identify and characterize CA patients that may have an odontogenic origin based on microbiologic, radiographic, and/or clinical findings. MATERIALS AND
methodsThis is a population-based cohort study analyzing retrospective and prospective data from CA patients. Radiographic examinations of panoramic radiographs (PRs) or computed tomography (CT) scans were conducted. CA patients characterized with odontogenic origin required the fulfilment of the following criteria on admission: (1) Oral pathologic conditions were the only bacterial infections present, (2) oral microorganisms were isolated in the purulent exudate from the brain, and (3) radiographically and/or clinical recordings of oral pathologic conditions.
resultsA total of 44 patients could be included in this study of which 25 (57%) were characterized as having CA with a likely odontogenic origin. Type two diabetes (T2D) (p = 0.014) and microorganisms of the Streptococcus anginosus group (SAG) (p < 0.01) were overrepresented in patients with CAs of odontogenic origin.
conclusionsOdontogenic infections may cause CAs to a greater extent than previously assumed. T2D was overrepresented among patients with odontogenic CA. When microorganisms of the SAG were isolated from the brain pus, CA patients had a predisposing odontogenic or sinus infection. CLINICAL RELEVANCE: The identification of patients with a likely odontogenic CA will contribute to understanding the etiology of the infectious disease and highlighting the importance of preserving oral health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.