Evidence map›Paper›PMID 37002412›Full record

ArticleBone marrow transplantation2023

Fludarabine/TBI 8 Gy versus fludarabine/treosulfan conditioning in patients with AML in first complete remission: a study from the Acute Leukemia Working Party of the EBMT.

Gesine Bug, Myriam Labopin, Riitta Niittyvuopio, Matthias Stelljes, Hans Christian Reinhardt, Inken Hilgendorf, Nicolaus Kröger, Ain Kaare, Wolfgang Bethge, Kerstin Schäfer-Eckart and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Bone marrow transplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 16 institutions in 8 countries.

Gesine BugGoethe University, Department of Medicine 2, Frankfurt am Main, Germany. g.bug@em.uni-frankfurt.de.ORCID 0000-0003-2359-131X
Myriam LabopinSorbonne University, Department of Hematology, Saint Antoine Hospital, INSERM UMR 938, Paris, France.ORCID 0000-0003-4514-4748
Riitta NiittyvuopioHUCH Comprehensive Cancer Center, Stem Cell Transplantation Unit, Helsinki, Finland.
Matthias StelljesUniversity of Muenster, Department of Hematology/Oncology, Muenster, Germany.ORCID 0000-0002-9331-5145
Hans Christian ReinhardtUniversity Hospital Essen, Department of Hematology and Stem Cell Transplantation, Essen, Germany.
Inken HilgendorfUniversitätsklinikum Jena, Klinik für Innere Medizin II (Abt. Hämatologie und Onkologie) Am Klinikum 1, Jena, Germany.ORCID 0000-0003-2038-9730
Nicolaus KrögerDepartment for Stem Cell Transplantation, University Medical Center, Hamburg, Germany.ORCID 0000-0001-5103-9966
Ain KaareTartu University Hospital, Clinic of Hematology and Oncology, Tartu, Estonia.ORCID 0000-0002-3170-1016
Wolfgang BethgeUniversität Tuebingen, Medizinische Klinik, Tuebingen, Germany.ORCID 0000-0001-6052-2618
Kerstin Schäfer-EckartKlinikum Nuernberg, 5. Medizinische Klinik, BMT-Unit, Nuernberg, Germany.
Mareike VerbeekTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Clinic and Policlinic for Internal Medicine III, Munich, Germany.
Stephan MielkeKarolinska Institutet and University Hospital, LabMed, CAST, Karolinska Comprehensive Cancer Center, Stockholm, Sweden.
Kristina CarlsonUniversity Hospital, Department of Haematology, Uppsala, Sweden.
Ali BazarbachiBone marrow Transplant Program, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.ORCID 0000-0002-7171-4997
Alexandros SpyridonidisBone Marrow Transplantation Division, University Hospital Patras, Patras, Greece.ORCID 0000-0003-3097-2532
Bipin N SavaniLong term Transplant Clinic, Vanderbilt University Medical Center, Nashville, TN, USA.
Arnon NaglerChaim Sheba Medical Center, Department of Bone Marrow Transplantation, Tel Hashomer, Israel.ORCID 0000-0002-0763-1265
Mohamad MohtySorbonne University, Department of Hematology, Saint Antoine Hospital, INSERM UMR 938, Paris, France.ORCID 0000-0002-7264-808X
Inserm · FRAmerican University of Beirut Medical Center · LBEssen University Hospital · DEGeneral University Hospital of Patras · GRGoethe University Frankfurt · DEKarolinska University Hospital · SEKlinikum Arnsberg · DEKlinikum Magdeburg · DESheba Medical Center · ILTartu University Hospital · EETUM Klinikum · DEUniversität Hamburg · DEUniversity of Münster · DEUniversity of Tübingen · DEUppsala University Hospital · SEVanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The optimal reduced intensity conditioning (RIC) regimen is a matter of debate. We retrospectively compared conditioning with fludarabine plus fractionated total body irradiation of 8 Gy (FluTBI) and fludarabine plus treosulfan 30, 36 or 42 g/m

Indexed as

Graft vs Host DiseaseHematopoietic Stem Cell TransplantationLeukemia, Myeloid, AcuteAcute DiseaseAdultBusulfanHumansMiddle AgedRecurrenceRetrospective StudiesTransplantation ConditioningVidarabineWhole-Body IrradiationBusulfanfludarabinetreosulfanVidarabine

Identifiers

PMID37002412
PMCPMC10247361
OpenAlexW4362459993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.