Evidence map›Paper›PMID 37002252›Full record

ArticleScientific reports2023

Morphological and histochemical identification of telocytes in adult yak epididymis.

Dapeng Yang, Ligang Yuan, Shaoyu Chen, Yong Zhang, Xiaojie Ma, Yindi Xing, Juanjuan Song

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Telocytes of the male reproductive system: dynamic tissue organizers.Frontiers in cell and developmental biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 3 countries.

Dapeng YangCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Ligang YuanCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China. yuan2918@126.com.
Shaoyu ChenCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Yong ZhangCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Xiaojie MaCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Yindi XingCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Juanjuan SongCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Gansu Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Telocytes (TCs) are a newly discovered type of mesenchymal cell that are closely related to the tissue's internal environment. The study aimed to investigate the morphological identification of TCs in the epididymis of adult yak and their role in the local microenvironment. In this study, transmission electron microscopy (TEM), scanning electron microscopy, immunofluorescence, qRT-PCR, and western blotting were used to analyze the cell morphology of TCs. The results showed that there are two types of TCs in the epididymal stroma of yak by TEM; one type is distributed around the capillaries with full cell bodies, longer TPs, and a large number of secretory vesicles; the other is distributed outside the basement membrane with irregularly long, striped, large nuclei and short telopodes (TPs). In addition, these TCs formed complex TC cell networks through TPs with epididymal interstitial capillaries and basal fibroblasts. TCs often appear near the capillaries and basement membrane by special staining. The surface markers of TCs (CD34, vimentin, and CD117) were positively expressed in the epididymal stroma and epithelium by immunohistochemistry, and immunofluorescence co-expression of vimentin + CD34 and CD117 + CD34 was observed on the surface of TCs. The trends in the mRNA and protein expression of TCs surface markers revealed expression was highest in the caput epididymis. In summary, this is first report of TCs in the epididymis of yak, and two phenotypes of TCs were observed. The existence and distribution characteristics of TCs in the epididymis of plateau yaks provide important clues for further study of the adaptation to reproductive function in the plateau.

Indexed as

EpididymisTelocytesAnimalsAntigens, CD34CattleImmunohistochemistryMaleTelopodesVimentinAntigens, CD34Vimentin

Identifiers

PMID37002252
PMCPMC10066225
OpenAlexW4362468682

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.