Evidence map›Paper›PMID 37000965›Full record

ReviewAnnual review of biomedical engineering2023

Nanotechnologies for Physiology-Informed Drug Delivery to the Lymphatic System.

Katharina Maisel, Claire A McClain, Amanda Bogseth, Susan N Thomas

Abstract readReview
In one paragraph

Review in Annual review of biomedical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katharina MaiselFischell Department of Bioengineering, University of Maryland, College Park, Maryland, USA; email: maiselka@umd.edu.
Claire A McClainWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA; email: susan.thomas@gatech.edu.
Amanda BogsethFischell Department of Bioengineering, University of Maryland, College Park, Maryland, USA; email: maiselka@umd.edu.
Susan N ThomasWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA; email: susan.thomas@gatech.edu.

Funding

Research Training Program Plan on Cell and Tissue Engineering (CTEng)T32GM008433 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI GARCIA, ANDRES J · 1991 to 2021
$7.1M
Lymph node-targeted multistage chemoimmunotherapy for lymphomaR01CA247484 · NCI · GEORGIA INSTITUTE OF TECHNOLOGY · PI FINN, M.G., THOMAS, SUSAN NAPIER · 2020 to 2024
$2.6M
Regulation and modeling of transport across tissue barriersR35GM142835 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI MAISEL, KATHARINA · 2021 to 2025
$2.0M
Melanoma immunotherapy targeting sentinel lymph nodesR01CA207619 · NCI · GEORGIA INSTITUTE OF TECHNOLOGY · PI THOMAS, SUSAN NAPIER · 2016 to 2020
$2.0M
NCI NIH HHS R01 CA207619NCI NIH HHS R01 CA247484NIGMS NIH HHS R35 GM142835NIGMS NIH HHS T32 GM008433
6 · The paper itself

Abstract

Accompanying the increasing translational impact of immunotherapeutic strategies to treat and prevent disease has been a broadening interest across both bioscience and bioengineering in the lymphatic system. Herein, the lymphatic system physiology, ranging from its tissue structures to immune functions and effects, is described. Design principles and engineering approaches to analyze and manipulate this tissue system in nanoparticle-based drug delivery applications are also elaborated.

Indexed as

BioengineeringDrug Delivery SystemsHumansLymphatic SystemNanotechnologybioengineeringbiomaterialsdrug delivery systemimmunoengineeringlymph nodetargeted delivery

Identifiers

PMID37000965
PMCPMC10879987

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.