Evidence map›Paper›PMID 37000895›Full record

ReviewAnnals of clinical and translational neurology2023

Attack phenotypes and disease course in pediatric MOGAD.

Jonathan D Santoro, Timothy Beukelman, Cheryl Hemingway, Suvi R K Hokkanen, Frank Tennigkeit, Tanuja Chitnis

Open access · goldAbstract readReview
In one paragraph

Review in Annals of clinical and translational neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Successful treatment with efgartigimod as rescue therapy in acute attack of MOGAD: a case report.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
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  8. Review
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  12. Article
  13. Review
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  15. Review
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  18. Review
  19. Impact of autoantibodies against myelin oligodendrocyte glycoprotein in paediatric acquired demyelinating disease: Intellectual functioning and academic performance.European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Jonathan D SantoroDivision of Neuroimmunology, Department of Pediatrics, Children's Hospital Los Angeles, Los Angeles, California, USA.ORCID 0000-0002-8350-8234
Timothy BeukelmanEpi Excellence LLC, Garnet Valley, Pennsylvania, USA.ORCID 0000-0001-9463-6306
Cheryl HemingwayGreat Ormond Street Hospital for Children, London, UK.
Suvi R K HokkanenUCB Pharma, Brussels, Belgium.
Frank TennigkeitUCB Biosciences, Monheim, Germany.
Tanuja ChitnisDepartment of Neurology, Mass General Brigham, Boston, Massachusetts, USA.ORCID 0000-0002-9897-4422
Great Ormond Street Hospital · GBMass General Brigham · USUCB Pharma (Belgium) · BEUCB Pharma (Germany) · DEUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is an autoimmune demyelinating condition that affects children differently than adults. We performed a literature review to assess the presentation and clinical course of pediatric MOGAD. The most common initial phenotype is acute disseminated encephalomyelitis, especially among children younger than five years, followed by optic neuritis (ON) and/or transverse myelitis. Approximately one-quarter of children with MOGAD have at least one relapse that typically occurs within three years of disease onset and often includes ON, even if ON was not present at onset. Clinical risk factors for a relapsing course have not been elucidated.

Indexed as

AutoantibodiesOptic NeuritisDisease ProgressionHumansMyelin-Oligodendrocyte GlycoproteinNeoplasm Recurrence, LocalPhenotypeAutoantibodiesMyelin-Oligodendrocyte Glycoprotein

Identifiers

PMID37000895
PMCPMC10187731
OpenAlexW4362458354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.