Evidence map›Paper›PMID 37000609›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2023

Cardiovascular and cerebral vascular health in females with postacute sequelae of COVID-19.

Damsara Nandadeva, Rachel J Skow, Brandi Y Stephens, Ann-Katrin Grotle, Stephanie Georgoudiou, Surendra Barshikar, Yaewon Seo, Paul J Fadel

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Damsara NandadevaDepartment of Kinesiology, University of Texas at Arlington, Arlington, Texas, United States.ORCID 0000-0002-9635-1117
Rachel J SkowDepartment of Kinesiology, University of Texas at Arlington, Arlington, Texas, United States.ORCID 0000-0002-0163-9792
Brandi Y StephensDepartment of Kinesiology, University of Texas at Arlington, Arlington, Texas, United States.ORCID 0000-0002-1624-8778
Ann-Katrin GrotleDepartment of Kinesiology, University of Texas at Arlington, Arlington, Texas, United States.ORCID 0000-0003-2990-8744
Stephanie GeorgoudiouDepartment of Graduate Nursing, College of Nursing and Health Innovation, University of Texas at Arlington, Arlington, Texas, United States.
Surendra BarshikarDepartment of Physical Medicine and Rehabilitation, University of Texas Southwestern Medical Center, Dallas, Texas, United States.ORCID 0000-0003-2509-1968
Yaewon SeoDepartment of Graduate Nursing, College of Nursing and Health Innovation, University of Texas at Arlington, Arlington, Texas, United States.
Paul J FadelDepartment of Kinesiology, University of Texas at Arlington, Arlington, Texas, United States.ORCID 0000-0002-0115-0743
The University of Texas at Arlington · USThe University of Texas Southwestern Medical Center · USUniversity of Peradeniya · LKWestern Norway University of Applied Sciences · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many individuals who had coronavirus disease 2019 (COVID-19) develop detrimental persistent symptoms, a condition known as postacute sequelae of COVID-19 (PASC). Despite the elevated risk of cardiovascular disease following COVID-19, limited studies have examined vascular function in PASC with equivocal results reported. Moreover, the role of PASC symptom burden on vascular health has not been examined. We tested the hypothesis that peripheral and cerebral vascular function would be blunted and central arterial stiffness would be elevated in patients with PASC compared with age-matched controls. Furthermore, we hypothesized that impairments in vascular health would be greater in those with higher PASC symptom burden. Resting blood pressure (BP; brachial and central), brachial artery flow-mediated dilation (FMD), forearm reactive hyperemia, carotid-femoral pulse wave velocity (PWV), and cerebral vasodilator function were measured in 12 females with PASC and 11 age-matched female controls without PASC. The severity of persistent symptoms in those with PASC was reported on a scale of 1-10 (higher score: greater severity). Brachial BP (e.g., systolic BP, 126 ± 19 vs.109 ± 8 mmHg;

Indexed as

COVID-19HyperemiaVascular StiffnessBlood PressureBrachial ArteryFemaleHumansPulse Wave AnalysisVasodilator AgentsVasodilator Agentsarterial stiffnessblood pressurecerebral vascular functionflow-mediated dilationlong COVID

Identifiers

PMID37000609
PMCPMC10151056
OpenAlexW4362457725

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.