Evidence map›Paper›PMID 37000531›Full record

ArticleJournal of materials chemistry. B2023

Ultrasmall superparamagnetic iron oxide nanoparticles for enhanced tumor penetration.

Xue Feng, Yuxiang Xue, Sevil Gonca, Kunlang Ji, Mei Zhang, Francisco R García-García, Quan Li, Yi Huang, Konstantin V Kamenev, Xianfeng Chen

Abstract read
In one paragraph

Article in Journal of materials chemistry. B, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xue FengSchool of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh, EH9 3JL, UK. Michael.Chen@ed.ac.uk.
Yuxiang XueSchool of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh, EH9 3JL, UK. Michael.Chen@ed.ac.uk.
Sevil GoncaSchool of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh, EH9 3JL, UK. Michael.Chen@ed.ac.uk.
Kunlang JiSchool of Chemistry, Centre for Science at Extreme Conditions, University of Edinburgh, The King's Buildings, Edinburgh, EH9 3FD, UK.
Mei ZhangSchool of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh, EH9 3JL, UK. Michael.Chen@ed.ac.uk.
Francisco R García-GarcíaSchool of Engineering, Institute for Materials and Processes, University of Edinburgh, The King's Buildings, Edinburgh, EH9 3JL, UK.ORCID 0000-0001-7336-273X
Quan LiSchool of Engineering, Institute for Energy Systems, University of Edinburgh, The King's Buildings, Edinburgh, EH9 3JL, UK.
Yi HuangSchool of Engineering, Institute for Materials and Processes, University of Edinburgh, The King's Buildings, Edinburgh, EH9 3JL, UK.ORCID 0000-0003-0733-3513
Konstantin V KamenevSchool of Engineering, Institute for Materials and Processes, University of Edinburgh, The King's Buildings, Edinburgh, EH9 3JL, UK.
Xianfeng ChenSchool of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh, EH9 3JL, UK. Michael.Chen@ed.ac.uk.ORCID 0000-0002-3189-2756

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intrinsic pathological characteristics of tumor microenvironments restrict the deep penetration of nanomedicines by passive diffusion. Magnetophoresis is a promising strategy to improve the tumor penetration of nanomedicines aided by the external magnetic propulsive force. However, the research thus far has been focused on large nanoparticles, while ultrasmall superparamagnetic iron oxide (Fe

Indexed as

Magnetite NanoparticlesMetal NanoparticlesCell Line, TumorDiffusionFerric CompoundsFerric Compoundsferric oxideMagnetite Nanoparticles

Identifiers

PMID37000531
PMCPMC10091360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.