Evidence map›Paper›PMID 37000216›Full record

Observational studyAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2023

Exploring the Multidimensional Relationship Between Medication Beliefs and Adherence to Medications Among Older Adults Living With Multimorbidity Using Polynomial Regression: An Observational Cohort Study.

Louise Foley, Ann S Doherty, Emma Wallace, Fiona Boland, Lisa Hynes, Andrew W Murphy, Gerard J Molloy

Open access · hybridAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Louise FoleySchool of Psychology, University of Galway, Galway, Ireland.ORCID 0000-0002-0773-3712
Ann S DohertyDepartment of General Practice, University College Cork, Cork, Ireland.ORCID 0000-0003-4149-1574
Emma WallaceDepartment of General Practice, University College Cork, Cork, Ireland.ORCID 0000-0002-9315-2956
Fiona BolandHRB Centre for Primary Care Research, Royal College of Surgeons in Ireland University of Medicine and Health Sciences, Dublin, Ireland.ORCID 0000-0003-3228-0046
Lisa HynesCroi Heart and Stroke Charity, Galway, Ireland.ORCID 0000-0003-0419-2188
Andrew W MurphyDiscipline of General Practice, University of Galway, Galway, Ireland.ORCID 0000-0001-5549-8246
Gerard J MolloySchool of Psychology, University of Galway, Galway, Ireland.ORCID 0000-0002-7718-9898
Ollscoil na Gaillimhe – University of Galway · IEUniversity College Cork · IECroí · IERoyal College of Surgeons in Ireland · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople living with multimorbidity may hold complex beliefs about medicines, potentially influencing adherence. Polynomial regression offers a novel approach to examining the multidimensional relationship between medication beliefs and adherence, overcoming limitations associated with difference scores. PURPOSE: To explore the multidimensional relationship between medication beliefs and adherence among people living with multimorbidity.

methodsSecondary analysis was conducted using observational data from a cohort of older adults living with ≥2 chronic conditions, recruited from 15 family practices in Ireland in 2010 (n = 812) and followed up in 2012 (n = 515). Medication beliefs were measured with the Beliefs about Medicines Questionnaire-Specific. Adherence was assessed with the medication possession ratio using prescription data from the national primary care reimbursement service. Polynomial regression was used to explore the best-fitting multidimensional models for the relationship between (i) beliefs and adherence at baseline, and (ii) beliefs at baseline and adherence at follow-up.

resultsConfirmatory polynomial regression rejected the difference-score model, and exploratory polynomial regression indicated quadratic models for both analyses. Reciprocal effects were present in both analyses (slope [Analysis 1]: β = 0.08, p = .007; slope [Analysis 2]: β = 0.07, p = .044), indicating that adherence was higher when necessity beliefs were high and concern beliefs were low. Nonreciprocal effects were also present in both analyses (slope [Analysis 1]: β = 0.05, p = .006; slope [Analysis 2]: β = 0.04, p = .043), indicating that adherence was higher when both necessity and concern beliefs were high.

conclusionsAmong people living with multimorbidity, there is evidence that the relationship between medication beliefs and adherence is multidimensional. Attempts to support adherence should consider the combined role of necessity and concern beliefs.

Indexed as

Health Knowledge, Attitudes, PracticeMultimorbidityAgedCohort StudiesHumansMedication AdherenceSurveys and QuestionnairesBeliefs about medicinesMedication adherenceMultimorbidityNecessity-Concerns FrameworkPolynomial regression

Identifiers

PMID37000216
PMCPMC10312300
OpenAlexW4362459506

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.