Evidence map›Paper›PMID 36999932›Full record

ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2023

Modelling eye lengths and refractions in the periphery.

Ramkumar Ramamirtham, James D Akula, Amber-Lee K Curran, Justyna Szczygiel, Annie M Lancos, Rafael Grytz, R Daniel Ferguson, Anne B Fulton

Open access · greenAbstract read
In one paragraph

Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ramkumar RamamirthamOphthalmology, Boston Children's Hospital, Boston, Massachusetts, USA.ORCID 0009-0009-4852-7219
James D AkulaOphthalmology, Boston Children's Hospital, Boston, Massachusetts, USA.ORCID 0000-0001-8049-1812
Amber-Lee K CurranOphthalmology, Boston Children's Hospital, Boston, Massachusetts, USA.
Justyna SzczygielOphthalmology, Boston Children's Hospital, Boston, Massachusetts, USA.
Annie M LancosOphthalmology, Boston Children's Hospital, Boston, Massachusetts, USA.
Rafael GrytzOphthalmology and Visual Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0001-9539-4070
R Daniel FergusonFerguson RD, LLC, Melrose, Massachusetts, USA.
Anne B FultonOphthalmology, Boston Children's Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-5752-2614
Boston Children's Hospital · USFerguson Library · USUniversity of Alabama at Birmingham · US

Funding

Photoreceptor Function in ROPR01EY010597 · NEI · CHILDREN'S HOSPITAL BOSTON · PI FULTON, ANNE B · 1994 to 2023
$10.7M
Scleral Remodeling in MyopiaR01EY026588 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Rafael Grytz · 2016 to 2026
$4.1M
Noninvasive Protection Against Retinopathy of PrematurityR01EY028953 · NEI · BOSTON CHILDREN'S HOSPITAL · PI AKULA, JAMES DANIEL · 2019 to 2021
$1.3M
NEI NIH HHS R01 EY010597NEI NIH HHS R01 EY026588NEI NIH HHS R01 EY028953
6 · The paper itself

Abstract

purposeTo create a simplified model of the eye by which we can specify a key optical characteristic of the crystalline lens, namely its power.

methodsCycloplegic refraction and axial length were obtained in 60 eyes of 30 healthy subjects at eccentricities spanning 40° nasal to 40° temporal and were fitted with a three-dimensional parabolic model. Keratometric values and geometric distances to the cornea, lens and retina from 45 eyes supplied a numerical ray tracing model. Posterior lens curvature (PLC) was found by optimising the refractive data using a fixed lens equivalent refractive index (

resultsEccentric refractive errors were relatively hyperopic in eyes with central refractions ≤-1.44 D but relatively myopic in emmetropes and hyperopes. Posterior lens power, which cannot be measured directly, was derived from the optimised model lens. There was a weak, negative association between derived PLC and central spherical equivalent refraction. Regardless of refractive error, the posterior retinal curvature remained fixed.

conclusionsBy combining both on- and off-axis refractions and eye length measurements, this simplified model enabled the specification of posterior lens power and captured off-axis lenticular characteristics. The broad distribution in off-axis lens power represents a notable contrast to the relative stability of retinal curvature.

Indexed as

Contact LensesHyperopiaMyopiaRefractive ErrorsEyeHumansRefraction, OcularRetinahyperopiamyopiaoptics

Identifiers

PMID36999932
PMCPMC11732252
OpenAlexW4362457707

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.