Evidence map›Paper›PMID 36999615›Full record

ArticleOncology reports2023

CircRPPH1 accelerates the proliferation and migration of bladder cancer via enhancing the STAT3 signaling pathway.

Xiao Liu, Yonghua Tong, Qiu Huang, Yu He, Haojie Shang, Zhiqiang Chen, Kun Tang

Abstract read
In one paragraph

Article in Oncology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiao LiuDepartment of Urology, Tongji Hospital, Tongji medical college, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China.
Yonghua TongDepartment of Urology, Tongji Hospital, Tongji medical college, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China.
Qiu HuangDepartment of Urology, Tongji Hospital, Tongji medical college, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China.
Yu HeDepartment of Urology, Tongji Hospital, Tongji medical college, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China.
Haojie ShangDepartment of Urology, Tongji Hospital, Tongji medical college, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China.
Zhiqiang ChenDepartment of Urology, Tongji Hospital, Tongji medical college, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China.
Kun TangDepartment of Urology, Tongji Hospital, Tongji medical college, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bladder cancer (BCa) is a common malignant disease with high recurrence and variable prognosis. Circular RNAs (circRNAs) are implicated in the development of multiple diseases. However, the biological activities of circRNAs in BCa remain largely elusive. In the present study, it was found that circRPPH1 was upregulated in BCa cell lines compared with normal urothelial cells. CircRPPH1 downregulation could inhibit the proliferation, migration and invasion of BCa cells

Indexed as

MicroRNAsUrinary Bladder NeoplasmsCell Line, TumorCell MovementCell ProliferationGene Expression Regulation, NeoplasticHumansRNA, CircularSignal TransductionSTAT3 Transcription FactorMicroRNAsMIRN296 microRNA, humanRNA, CircularSTAT3 protein, humanSTAT3 Transcription Factorbladder cancercircRPPH1circular RNAfunctionSTAT3

Identifiers

PMID36999615
PMCPMC10091079

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.