Evidence map›Paper›PMID 36999313›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2023

Role of Cerebral Imaging on Diagnosis and Management in Patients With Suspected Infective Endocarditis.

Matthaios Papadimitriou-Olivgeris, Benoit Guery, Nicoleta Ianculescu, Vincent Dunet, Yosra Messaoudi, Silvia Pistocchi, Piergiorgio Tozzi, Matthias Kirsch, Pierre Monney

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Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Matthaios Papadimitriou-OlivgerisInfectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-0565-5105
Benoit GueryInfectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Nicoleta IanculescuDepartment of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Vincent DunetDepartment of Medical Radiology, Service of Diagnostic and Interventional Radiology, Neuroradiology Unit, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Yosra MessaoudiDepartment of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Silvia PistocchiDepartment of Medical Radiology, Service of Diagnostic and Interventional Radiology, Neuroradiology Unit, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Piergiorgio TozziDepartment of Cardiac Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Matthias KirschDepartment of Cardiac Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Pierre MonneyDepartment of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCerebral embolic events (CEEs) are common complications of infective endocarditis (IE), and their presence can modify diagnosis and therapeutic plans. The aim of the present study was to assess the role of cerebral imaging (Cer-Im) on diagnosis and management of patients with suspected IE.

methodsThis study was conducted at the Lausanne University Hospital, Lausanne, Switzerland, from January 2014 to June 2022. CEEs and IE were defined according to modified Duke criteria of the European Society of Cardiology (ESC) guidelines.

resultsAmong 573 patients with IE suspicion and Cer-Im, 239 (42%) patients had neurological symptoms. At least 1 CEE was found in 254 (44%) episodes. Based on Cer-Im findings, episodes were reclassified from rejected to possible or from possible to definite IE in 3 (1%) and 25 (4%) patients, respectively (0% and 2% in asymptomatic patients, respectively). Among the 330 patients with possible or definite IE, at least 1 CEE was found in 187 (57%) episodes. A new surgical indication (in association with left-side vegetation >10 mm) was established in 74/330 (22%) IE patients and 30/155 (19%) asymptomatic IE patients, respectively.

conclusionsCer-Im in asymptomatic patients with IE suspicion showed limited potential for improving the diagnosis of IE. In contrast, performing Cer-Im in asymptomatic patients with IE may be useful for decision making, because Cer-Im findings led to the establishment of new operative indication for valvular surgery in one fifth of patients according to ESC guidelines.

Indexed as

EndocarditisEndocarditis, BacterialHumansSwitzerlandembolizationinfective endocarditisischemic lesionsMRIvalve surgery

Identifiers

PMID36999313
PMCPMC10425197

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.