Evidence map›Paper›PMID 36999158›Full record

ArticleNeural plasticity2023

Diet Control and Swimming Exercise Ameliorate HFD-Induced Cognitive Impairment Related to the SIRT1-NF-

Wei Wei, Zhicheng Lin, PeiTao Xu, Xinru Lv, Libin Lin, Yongxu Li, Yangjie Zhou, Taotao Lu, Xiehua Xue

Open access · goldFull text read
In one paragraph

Article in Neural plasticity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Wei WeiThe Affiliated Rehabilitation Hospital, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Zhicheng LinThe Affiliated Rehabilitation Hospital, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
PeiTao XuThe Affiliated Rehabilitation Hospital, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Xinru LvCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Libin LinCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Yongxu LiCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Yangjie ZhouCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Taotao LuCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Xiehua XueThe Affiliated Rehabilitation Hospital, Fujian University of Traditional Chinese Medicine, Fuzhou, China.ORCID 0000-0002-9018-1436
Fujian University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-fat diet- (HFD-) induced neuroinflammation may ultimately lead to an increased risk of cognitive impairment. Here, we evaluate the effects of diet control and swimming or both on the prevention of cognitive impairment by enhancing SIRT1 activity. Twenty-week-old ApoE-/- mice were fed a HFD for 8 weeks and then were treated with diet control and/or swimming for 8 weeks. Cognitive function was assessed using the novel object recognition test (NORT) and Y-maze test. The expression of sirtuin-1 (SIRT1), peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1

Indexed as

Cognitive DysfunctionNF-kappa BAnimalsApolipoproteins EBrain-Derived Neurotrophic FactorDietDiet, High-FatDiffusion Tensor ImagingMiceMice, Knockout, ApoENeuroinflammatory DiseasesPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaSirtuin 1SwimmingTumor Necrosis Factor-alphaApolipoproteins EBrain-Derived Neurotrophic FactorNF-kappa BPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaSirt1 protein, mouseSirtuin 1Tumor Necrosis Factor-alpha

Identifiers

PMID36999158
PMCPMC10049848
OpenAlexW4328052531

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read17
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.