ArticleMicrosystems & nanoengineering2023
Dual-signal readout paper-based wearable biosensor with a 3D origami structure for multiplexed analyte detection in sweat.
Article in Microsystems & nanoengineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 86 citations in OpenAlex.
- Microfluidic valves for wearable sweat analysis: a review.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026Review
- Wearable Sensing for Clinical Physiology Monitoring: Emerging Paradigms.Physiology (Bethesda, Md.) · 2026Review
- From Single-Ion to Integrated Multi-Ion Platforms: Wearable Sweat Sensors for Electrolyte Monitoring.Biosensors · 2026Review
- Enhanced Piezoelectric Effect in P(VDF-TrFE) through Synergistic Templating by PEDOT:PSS and Paper.ACS applied electronic materials · 2026Article
- Human motion recognition and prediction using loose cloth.Nature communications · 2026Article
- Review
- A Sweat Cortisol Sensor Based on Gold-Modified Molecularly Imprinted Polymer.Nanomaterials (Basel, Switzerland) · 2025Article
- Microfluidic technologies for wearable and implantable biomedical devices.Lab on a chip · 2025Review
- Sweat-Sensing Patches with Integrated Hydrogel Interface for Resting Sweat Collection and Multi-Information Detection.Biosensors · 2025Article
- Recent Advances in Paper-Based Electronics: Emphasis on Field-Effect Transistors and Sensors.Biosensors · 2025Review
- Advancements in Wearable and Implantable BioMEMS Devices: Transforming Healthcare Through Technology.Micromachines · 2025Review
- Self-Tuning Reaction Conditioning of a Paper-Based Electrochemical Biosensor for Acetaldehyde Detection.ACS omega · 2025Article
- Machine learning in point-of-care testing: innovations, challenges, and opportunities.Nature communications · 2025Review
- Biomaterials for reliable wearable health monitoring: Applications in skin and eye integration.Biomaterials · 2025Review
- Fe/Pt-doped carbon nanoparticles with peroxidase-like activity for point-of-care determination of uric acid.Mikrochimica acta · 2024Article
- A Paper-Based Wearable Moist-Electric Generator for Sustained High-Efficiency Power Output and Enhanced Moisture Capture.Small (Weinheim an der Bergstrasse, Germany) · 2024Article
- Recent Advances in the Fabrication and Application of Electrochemical Paper-Based Analytical Devices.Biosensors · 2024Review
- Ambient energy harvesters in wearable electronics: fundamentals, methodologies, and applications.Journal of nanobiotechnology · 2024Review
- 3D-Printed Flexible Microfluidic Health Monitor forACS sensors · 2024Article
- Sustainable Sensing with Paper Microfluidics: Applications in Health, Environment, and Food Safety.Biosensors · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this research, we design and implement a small, convenient, and noninvasive paper-based microfluidic sweat sensor that can simultaneously detect multiple key biomarkers in human sweat. The origami structure of the chip includes colorimetric and electrochemical sensing regions. Different colorimetric sensing regions are modified with specific chromogenic reagents to selectively identify glucose, lactate, uric acid, and magnesium ions in sweat, as well as the pH value. The regions of electrochemical sensing detect cortisol in sweat by molecular imprinting. The entire chip is composed of hydrophilically and hydrophobically treated filter paper, and 3D microfluidic channels are constructed by using folding paper. The thread-based channels formed after the hydrophilic and hydrophobic modifications are used to control the rate of sweat flow, which in turn can be used to control the sequence of reactions in the differently developing colored regions to ensure that signals of the best color can be captured simultaneously by the colorimetric sensing regions. Finally, the results of on-body experiments verify the reliability of the proposed sweat sensor and its potential for the noninvasive identification of a variety of sweat biomarkers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.