Evidence map›Paper›PMID 36998780›Full record

ArticleFrontiers in neurology2023

Developmental changes in brain activity of heterozygous

Mayu Tahara, Norimichi Higurashi, Junichi Hata, Masako Nishikawa, Ken Ito, Shinichi Hirose, Takehito Kaneko, Tomoji Mashimo, Tetsushi Sakuma, Takashi Yamamoto and 1 more

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Mayu TaharaDepartment of Pediatrics, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Norimichi HigurashiDepartment of Pediatrics, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Junichi HataDivision of Regenerative Medicine, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Masako NishikawaClinical Research Support Center, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Ken ItoDepartment of Pediatrics, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Shinichi HiroseGeneral Medical Research Center, School of Medicine, Fukuoka University, Fukuoka, Japan.
Takehito KanekoDivision of Fundamental and Applied Sciences, Graduate School of Science and Engineering, Iwate University, Morioka, Japan.
Tomoji MashimoDivision of Animal Genetics, Laboratory Animal Research Center, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo, Japan.
Tetsushi SakumaDivision of Integrated Sciences for Life, Graduate School of Integrated Sciences for Life, Hiroshima University, Hiroshima, Japan.
Takashi YamamotoDivision of Integrated Sciences for Life, Graduate School of Integrated Sciences for Life, Hiroshima University, Hiroshima, Japan.
Hirotaka James OkanoDivision of Regenerative Medicine, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Jikei University School of Medicine · JPHiroshima University · JPFukuoka University · JPIwate University · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Dravet syndrome (DS) is an infantile-onset developmental and epileptic encephalopathy characterized by an age-dependent evolution of drug-resistant seizures and poor developmental outcomes. Functional impairment of gamma-aminobutyric acid (GABA)ergic interneurons due to loss-of-function mutation of Methods: We established an Results: Conclusions: In

Indexed as

bumetanide (BTN)developmental and epileptic encephalopathy (DEE)Dravet syndrome (DS)functional neuroimaginggamma-aminobutyric acid (GABA)

Identifiers

PMID36998780
PMCPMC10043303
OpenAlexW4324146448

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read1
measurements read138
identifiers read1
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.