Evidence map›Paper›PMID 36998704›Full record

ArticleEXCLI journal2023

Amount and composition of total fatty acids in red and yellow bone marrow are altered with changes in bone mineral density.

Sabrina Ehnert, Anna J Schreiner, Claudine Seeliger, Josef Ecker, Fabian Springer, Gerhard Liebisch, Philipp Hemmann, Tina Histing, Andreas K Nussler

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In one paragraph

Article in EXCLI journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sabrina EhnertSiegfried-Weller Institute for Trauma Research, BG Trauma Center, University of Tuebingen, Tuebingen, Germany.
Anna J SchreinerSiegfried-Weller Institute for Trauma Research, BG Trauma Center, University of Tuebingen, Tuebingen, Germany.
Claudine SeeligerZIEL Institute for Food & Health, Research Group Lipid Metabolism, Technical University of Munich, Freising, Germany.
Josef EckerZIEL Institute for Food & Health, Research Group Lipid Metabolism, Technical University of Munich, Freising, Germany.
Fabian SpringerDepartment of Diagnostic and Interventional Radiology, University Hospital and BG Trauma Center, University of Tuebingen, Tuebingen, Germany.
Gerhard LiebischInstitute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany.
Philipp HemmannSiegfried-Weller Institute for Trauma Research, BG Trauma Center, University of Tuebingen, Tuebingen, Germany.
Tina HistingSiegfried-Weller Institute for Trauma Research, BG Trauma Center, University of Tuebingen, Tuebingen, Germany.
Andreas K NusslerSiegfried-Weller Institute for Trauma Research, BG Trauma Center, University of Tuebingen, Tuebingen, Germany.
University Hospital Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is general consent that with decreasing bone mineral density the amount of marrow adipose tissue increases. While image-based techniques, claim an increase in saturated fatty acids responsible for this effect, this study shows an increase in both saturated and unsaturated fatty acids in the bone marrow. Using fatty acid methyl ester gas chromatography-mass spectrometry, characteristic fatty acid patterns for patients with normal BMD (N = 9), osteopenia (N = 12), and osteoporosis (N = 9) have been identified, which differ between plasma, red bone marrow and yellow bone marrow. Selected fatty acids,

Indexed as

bone marrowbone mineral densityfatty acid compositionsaturated fatty acidsTartrate-Resistant Acidic Phosphatase (TRAP5b)unsaturated fatty acids

Identifiers

PMID36998704
PMCPMC10043387
OpenAlexW4362458975

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read1
measurements read56
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.