Evidence map›Paper›PMID 36998623›Full record

ReviewFrontiers in psychiatry2023

Exploring psilocybin-assisted psychotherapy in the treatment of methamphetamine use disorder.

Jonathan Brett, Elizabeth Knock, P Todd Korthuis, Paul Liknaitzky, Kevin S Murnane, Christopher R Nicholas, James C Patterson, Christopher S Stauffer

Full text readReview
In one paragraph

Review in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Novel neurotherapeutic targets for substance use disorders: Neuroplasticity, neuroinflammation, gasotransmitters and non-canonical organ systems.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jonathan BrettDepartment of Clinical Pharmacology, St. Vincent's Hospital, Sydney, NSW, Australia.
Elizabeth KnockAlcohol and Drug Service, St. Vincent's Hospital, Sydney, NSW, Australia.
P Todd KorthuisSection of Addiction Medicine, Oregon Health & Science University, Portland, OR, United States.
Paul LiknaitzkyDepartment of Psychiatry, School of Clinical Sciences, Monash University, Caulfield, VIC, Australia.
Kevin S MurnaneLouisiana Addiction Research Center, Department of Pharmacology, Toxicology & Neuroscience, Shreveport, LA, United States.
Christopher R NicholasDepartment of Family Medicine and Community Health, University of Wisconsin-Madison, Madison, WI, United States.
James C PattersonLouisiana Addiction Research Center, Department of Pharmacology, Toxicology & Neuroscience, Shreveport, LA, United States.
Christopher S StaufferDepartment of Mental Health, Veterans Affairs Portland Health Care System, Portland, OR, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methamphetamine use disorder is a chronic relapsing condition associated with substantial mental, physical, and social harms and increasing rates of mortality. Contingency management and psychotherapy interventions are the mainstays of treatment but are modestly effective with high relapse rates, while pharmacological treatments have shown little to no efficacy. Psilocybin-assisted psychotherapy is emerging as a promising treatment for a range of difficult-to-treat conditions, including substance use disorders; however, no studies have yet been published looking at psilocybin-assisted psychotherapy in the treatment of methamphetamine use disorder. Here we review the rationale for psilocybin-assisted psychotherapy as a potential treatment for this indication, and describe practical considerations based on our early experience designing and implementing four separate clinical trials of psilocybin-assisted psychotherapy for methamphetamine use disorder.

Indexed as

Addiction Medicinemethamphetaminemethamphetamine use disorderpsilocybinpsilocybin-assisted psychotherapystimulant use disorder

Identifiers

PMID36998623
PMCPMC10043240

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read24
identifiers read5
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.