Evidence map›Paper›PMID 36998440›Full record

ArticleFrontiers in oncology2023

Response to selpercatinib in a patient with

Aakriti Arora, Jacob Zaemes, Metin Ozdemirli, Chul Kim

Open access · goldFull text readCase Reports
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. A favorable antitumor efficacy of sotorasib in a patient withInternational cancer conference journal · 2025
    Article
  5. Article
  6. Review
  7. First-line selpercatinib for a patient withRespiratory medicine case reports · 2024
    Article
  8. Article
  9. Cancers · 2023
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Aakriti AroraDepartment of Medicine, MedStar Washington Hospital Center, Washington, DC, United States.
Jacob ZaemesLombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, United States.
Metin OzdemirliDepartment of Pathology, MedStar Georgetown University Hospital, Washington, DC, United States.
Chul KimLombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, United States.
Georgetown University Medical Center · USMedStar Georgetown University Hospital · USMedStar Washington Hospital Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Large-cell neuroendocrine carcinoma (LCNEC) is a rare subtype of non-small-cell lung cancer associated with a poor prognosis. LCNEC is genetically heterogeneous, and studies have revealed distinct molecular subtypes of LCNEC, which may have therapeutic implications. Herein, we present a case of a patient with stage IV LCNEC harboring a

Indexed as

large cell neuroendocrine carcinomalung cancer (LC)RET fusionselpercatinibtargeted

Identifiers

PMID36998440
PMCPMC10046803
OpenAlexW4324144944

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read23
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.