ArticleEuropean journal of ophthalmology2023
Changes in corneal endothelial cell density after trabeculectomy.
Article in European journal of ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 7 citations in OpenAlex.
- Evaluation of Changes in Ocular Tissue Elasticity Before and After Trabeculectomy Using Shear Wave Elastography.Journal of clinical medicine · 2026Article
- Preoperative Use of the Rho Kinase Inhibitor Ripasudil Protects the Corneal Endothelium from Trabeculectomy-Induced Damage.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Long-term outcomes of Baerveldt glaucoma implants with the scleral flap and patch technique and vitreous cavity insertion: a 5-year follow-up.International ophthalmology · 2025Article
- Clinical characteristics and managements of severe corneal ulcers in patients with end-stage glaucoma.International ophthalmology · 2025Article
- One-year longitudinal study of corneal changes after different vitrectomy procedures using confocal microscopy.Scientific reports · 2025Article
- Decoding Corneal Endothelial Loss from Glaucoma Treatment: A Case-Control Stratification Analysis.Journal of current glaucoma practiceArticle
- Likelihood of Corneal Transplantation after Tube versus Trabeculectomy: An IRIS® Registry Study.Ophthalmology. GlaucomaArticle
- Risk factors for corneal endothelial cell loss after phacoemulsification.Taiwan journal of ophthalmologyArticle
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGlaucoma is a leading cause of blindness worldwide for which trabeculectomy is the most effective surgical intervention for advanced disease. However, trabeculectomy has been associated with alterations to corneal endothelium, including a decrease in corneal endothelial cell density (CECD). The purpose of this study was to investigate changes in CECD after trabeculectomy, and identify factors contributing to cell loss, such as pre-operative biometry and lens status.
methodsThis retrospective study included 72 eyes of 60 patients who underwent trabeculectomy between January 2018 and June 2021 at two private hospitals. Demographic and clinical data were obtained at baseline. Corneal specular microscopy was performed pre-operatively and at 6 months after surgery. CECD was evaluated and compared between groups to quantify changes to corneal endothelium and identify significant factors affecting decreases in cell density.
resultsMean CECD was 2284.66 ± 375.59 pre-operatively and 2129.52 ± 401.96 after 6 months (
conclusionsSignificant decreases in CECD occurred after trabeculectomy. Less corneal endothelial cell loss occurred in pseudophakic eyes. Hence, if patients need trabeculectomy and cataract surgery, it may be better to perform cataract surgery first. Longer term studies should derive more information.
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