ArticlePlant communications2023
Synthetic dual hormone-responsive promoters enable engineering of plants with broad-spectrum resistance.
Article in Plant communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- Fruit-Specific Promoters in Plants: Advances, Regulatory Mechanisms and Applications in Plant Biotechnology.Plants (Basel, Switzerland) · 2026Review
- GhPsbO breaks the growth-immunity tradeoff by simultaneously promoting growth and defense in cotton.The Plant cell · 2026Article
- Chloroplast-to-apoplast relocalization of MOC1 strengthens plant vascular immunity.Horticulture research · 2026Article
- Exploiting plant immune "switches" for resistance engineering.Stress biology · 2026Review
- Transcriptomic and physiological analyses reveal the molecular mechanisms underlying resistance to Cercospora beticola Sacc. (Cercospora leaf spot) in sugar beet.BMC plant biology · 2026Article
- A voyage of reprogrammable metabolic bioengineering reshapes plant defense: from editing tools to synthetic systems.Frontiers in plant science · 2026Review
- Synthetic promoter design in plants: integration of computational and experimental approaches.Frontiers in plant science · 2026Review
- BrHDA6 mediates nonhistone deacetylation of BrSOT12 to positively regulate downy mildew resistance inHorticulture research · 2025Article
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- Genetic engineering, including genome editing, for enhancing broad-spectrum disease resistance in crops.Plant communications · 2025Review
- Integrative hyperspectral, transcriptomic, and metabolomic analysis reveals the mechanism of tea plants in response to sooty mold disease.BMC plant biology · 2024Article
- Comparative transcriptome revealed the molecular responses of Aconitum carmichaelii Debx. to downy mildew at different stages of disease development.BMC plant biology · 2024Article
- The elicitor VP2 from Verticillium dahliae triggers defence response in cotton.Plant biotechnology journal · 2024Article
- Development of robust constitutive synthetic promoter using genetic resources of plant pararetroviruses.Frontiers in plant science · 2024Article
- Bibliometric and meta-analysis on the publication status, research trends and impact inducing factors of JA-SA interactions in plants.Frontiers in plant science · 2024Article
- Advances in Roles of Salicylic Acid in Plant Tolerance Responses to Biotic and Abiotic Stresses.Plants (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In plant immunity, the mutually antagonistic hormones salicylic acid (SA) and jasmonic acid (JA) are implicated in resistance to biotrophic and necrotrophic pathogens, respectively. Promoters that can respond to both SA and JA signals are urgently needed to engineer plants with enhanced resistance to a broad spectrum of pathogens. However, few natural pathogen-inducible promoters are available for this purpose. To address this problem, we have developed a strategy to synthesize dual SA- and JA-responsive promoters by combining SA- and JA-responsive cis elements based on the interaction between their cognate trans-acting factors. The resulting promoters respond rapidly and strongly to both SA and Methyl Jasmonate (MeJA), as well as different types of phytopathogens. When such a synthetic promoter was used to control expression of an antimicrobial peptide, transgenic plants displayed enhanced resistance to a diverse range of biotrophic, necrotrophic, and hemi-biotrophic pathogens. A dual-inducible promoter responsive to the antagonistic signals auxin and cytokinin was generated in a similar manner, confirming that our strategy can be used for the design of other biotically or abiotically inducible systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.