Evidence map›Paper›PMID 36998047›Full record

ArticleBMC health services research2023

Prevention of invasive ventilation (PRiVENT)-a prospective, mixed-methods interventional, multicentre study with a parallel comparison group: study protocol.

Julia D Michels, Jan Meis, Noemi Sturm, Florian Bornitz, Selina von Schumann, Aline Weis, Benjamin Neetz, Martina Bentner, Johanna Forstner, Nicola Litke and 12 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC health services research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05260853 (Early Detection and Early Intervention Program in High-risk Patients to Avoid Invasive Long-term Ventilation - Prevention of Invasive Ventilation - PRiVENT), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05260853 naunknown statusnot on this map

Early Detection and Early Intervention Program in High-risk Patients to Avoid Invasive Long-term Ventilation - Prevention of Invasive Ventilation - PRiVENT

TypeinterventionalSponsorFelix JF HerthRan2021 to 2024Enrolled1,500ConditionsInvasive Ventilation, WeaningArmsWeaning Board
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 20 institutions in 1 country.

Julia D Michels *Department of Pneumology and Critical Care, Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Thoraxklinik Heidelberg gGmbH, Heidelberg, Germany. Julia.Michels@med.uni-heidelberg.de.
Jan Meis *Institute of Medical Biometry, Heidelberg University, Heidelberg, Germany.
Noemi SturmDepartment of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany.
Florian BornitzAsklepios Hospital Barmbek, Pneumology and Internal Intensive Care Medicine, Hamburg, Germany.
Selina von SchumannDepartment of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany.
Aline WeisDepartment of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany.
Benjamin NeetzDepartment of Pneumology and Critical Care, Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Thoraxklinik Heidelberg gGmbH, Heidelberg, Germany.
Martina BentnerDepartment of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany.
Johanna ForstnerDepartment of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany.
Nicola LitkeDepartment of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany.
Michel WensingDepartment of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany.
Stella ErdmannInstitute of Medical Biometry, Heidelberg University, Heidelberg, Germany.
Thomas GrobeaQua Institute for Applied Quality Improvement and Research in Health Care, Göttingen, Germany.
Timm FrerkaQua Institute for Applied Quality Improvement and Research in Health Care, Göttingen, Germany.
Axel KempaDepartment of Pneumology and Critical Care, SLK-Klinik Löwenstein, Löwenstein, Germany.
Claus NeurohrDepartment of Pneumology and Respiratory Medicine, Robert-Bosch-Krankenhaus Klinik Schillerhöhe, Gerlingen, Germany.
Armin SchneiderDepartment of Anaesthesia and Intensive Care Medicine Waldburg-Zeil Kliniken, Wangen Im Allgäu, Germany.
Michael MüllerDepartment of Pneumology and Critical Care, Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Thoraxklinik Heidelberg gGmbH, Heidelberg, Germany.
Felix J F HerthDepartment of Pneumology and Critical Care, Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Thoraxklinik Heidelberg gGmbH, Heidelberg, Germany.
Joachim SzecsenyiDepartment of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany.
Franziska C TrudzinskiDepartment of Pneumology and Critical Care, Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Thoraxklinik Heidelberg gGmbH, Heidelberg, Germany.
PRiVENT-Study Group
Heidelberg University · DEGerman Center for Lung Research · DERobert Bosch Hospital · DELöwenstein Medical (Germany) · DESiloah St. Trudpert Klinikum · DEAsklepios Klinik Barmbek · DEUniversity Medical Centre Mannheim · DEKlinik Donaustauf · DECaritas-Krankenhaus Bad Mergentheim · DEDiakonie-Klinikum Stuttgart · DEGerman Society of Medical Intensive Care and Emergency Medicine · DEHegau-Bodensee-Klinikum Singen · DEImmanuel Klinikum Bernau · DEKlinikum Ingolstadt · DEKrankenhäuser Landkreis Freudenstadt · DELandwirtschaftlichen Zentrums Baden-Württemberg​ · DEOstalb-Klinikum Aalen · DESRH Klinikum Karlsbad-Langensteinbach · DEStädtisches Klinikum Karlsruhe · DEUnfallkrankenhaus Berlin · DE

Funding

the Federal Joint Committee (G-BA) 01NVF19023
6 · The paper itself

Abstract

backgroundInvasive mechanical ventilation (IMV) is a standard therapy for intensive care patients with respiratory failure. With increasing population age and multimorbidity, the number of patients who cannot be weaned from IMV increases, resulting in impaired quality of life and high costs. In addition, human resources are tied up in the care of these patients.

methodsThe PRiVENT intervention is a prospective, mixed-methods interventional, multicentre study with a parallel comparison group selected from insurance claims data of the health insurer Allgemeine Ortskrankenkasse Baden-Württemberg (AOK-BW) conducted in Baden-Württemberg, Germany, over 24 months. Four weaning centres supervise 40 intensive care units (ICUs), that are responsible for patient recruitment. The primary outcome, successful weaning from IMV, will be evaluated using a mixed logistic regression model. Secondary outcomes will be evaluated using mixed regression models. DISCUSSION: The overall objective of the PRiVENT project is the evaluation of strategies to prevent long-term IMV. Additional objectives aim to improve weaning expertise in and cooperation with the adjacent Intensive Care Units.

trial registrationThis study is registered at ClinicalTrials.gov (NCT05260853).

Indexed as

Noninvasive VentilationVentilator WeaningHumansLungMulticenter Studies as TopicProspective StudiesQuality of LifeRespiration, ArtificialInvasive mechanical ventilationMedical education and trainingRespiratory failureWeaningWeaning failure

Identifiers

PMID36998047
PMCPMC10061400
OpenAlexW4361274163

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.