ArticleBMC pediatrics2023
Experience in diagnosis and treatment of duodenal ulcer perforation in children.
Article in BMC pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.
- Perforated peptic ulcers in children: a systematic review.BMC pediatrics · 2025Pooled it
- Treatment outcomes and determinants of refractory peptic ulcer disease in children: A prospective study from Vietnam.Journal of pediatric gastroenterology and nutrition · 2026Article
- Duodenal perforation following right nephrectomy in a paraplegic patient with pyonephrosis: a case report and clinical insights.Frontiers in medicine · 2026Article
- A Rare Case of Concomitant Duodenal and Gallbladder Perforation in a Pediatric Patient.Cureus · 2025Article
- Gastrointestinal contrast-enhanced ultrasonography for diagnosis and treatment of peptic ulcer in children.World journal of gastroenterology · 2024Article
- Experience of management of pediatric upper gastrointestinal perforations: a series of 30 cases.Frontiers in pediatrics · 2023Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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Abstract
backgroundThis study aims to summarize our experience in diagnosis and treatment of pediatric duodenal ulcer perforation in a National Center for Children's Health.
methodsFifty-two children with duodenal perforation hospitalized in Beijing Children's Hospital Affiliated to Capital Medical University from January 2007 to December 2021 were retrospectively collected. According to the inclusion and exclusion criteria, patients with duodenal ulcer perforation were included in the group. They were divided into the surgery group and the conservative group according to whether they received surgery.
resultsA total of 45 cases (35 males and 10 females) were included, with a median age of 13.0 (0.3-15.4) years. Forty cases (40/45, 88.9%) were over 6 years old, and 31 (31/45, 68.9%) were over 12 years old. Among the 45 cases, 32 cases (32/45, 71.1%) were examined for Helicobacter pylori (HP), and 25 (25/32, 78.1%) were positive. There were 13 cases in the surgery group and 32 cases in the conservative group, without a significant difference in age between the two groups (P = 0.625). All cases in the surgery group and the conservative group started with abdominal pain. The proportion of history time within 24 h in the two groups was 6/13 and 12/32 (P = 0.739), and the proportion of fever was 11/13 and 21/32 (P = 0.362). The proportion of pneumoperitoneum in the surgery group was higher than that in the conservative group (12/13 vs. 15/32, P = 0.013). The fasting days in the surgery group were shorter than those in the conservative group (7.7 ± 2.92 vs. 10.3 ± 2.78 days, P = 0.014). There was no significant difference in the total hospital stay (13.6 ± 5.60 vs14.8 ± 4.60 days, P = 0.531). The operation methods used in the surgery group were all simple sutures through laparotomy (9 cases) or laparoscopy (4 cases). All patients recovered smoothly after surgery.
conclusionDuodenal ulcer perforation in children is more common in adolescents, and HP infection is the main cause. Conservative treatment is safe and feasible, but the fasting time is longer than the surgery group. A simple suture is the main management for the surgery group.
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