Evidence map›Paper›PMID 36997935›Full record

ArticleCardiovascular diabetology2023

Association between triglyceride glucose-body mass index and cardiovascular outcomes in patients undergoing percutaneous coronary intervention: a retrospective study.

Yang Cheng, Zhen Fang, Xinxin Zhang, Yuchen Wen, Jiaqi Lu, Shenghu He, Bing Xu

Open access · goldAbstract read
In one paragraph

Article in Cardiovascular diabetology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed, 2 pooled it
40.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

113 citing papers in PubMed, 2 syntheses or guidelines pooled it, 185 citations in OpenAlex.

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53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yang Cheng *Clinical Medical College, Yangzhou University, Yangzhou, 225001, China.
Zhen Fang *Clinical Medical College, Yangzhou University, Yangzhou, 225001, China.
Xinxin ZhangClinical Medical College, Yangzhou University, Yangzhou, 225001, China.
Yuchen WenClinical Medical College, Yangzhou University, Yangzhou, 225001, China.
Jiaqi LuClinical Medical College, Yangzhou University, Yangzhou, 225001, China.
Shenghu HeClinical Medical College, Yangzhou University, Yangzhou, 225001, China. yzhshys@163.com.
Bing XuClinical Medical College, Yangzhou University, Yangzhou, 225001, China. nyxb1980@163.com.
Yangzhou University · CNDalian Medical University · CNNorthern Jiangsu People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe triglyceride glucose-body mass index (TyG-BMI index) has been considered a reliable surrogate measure of insulin resistance; however, its ability to predict the incidence of cardiovascular disease in individuals with coronary artery disease (CAD) remains uncertain. The aim of this study was to demonstrate the correlation between the TyG-BMI index and cardiovascular incidence.

methodsA total of 2533 consecutive participants who underwent percutaneous coronary intervention (PCI) and drug-eluting stent (DES) implantation were included. Data from 1438 patients was analyzed in the study. The endpoint was defined as a composite of acute myocardial infarction, repeat revascularization, stroke, and all-cause mortality (major adverse cardiac and cerebrovascular events, MACCEs) at 34-month follow-up. The formula for calculating the TyG-BMI index is ln [fasting triglyceride (mg/dL) × fasting blood glucose (mg/dL)/2] × BMI.

resultsAmong the 1438 participants, 195 incident patient cases of MACCEs were ascertained. The incidence of MACCEs showed no statistically significant differences in the TyG-BMI index tertiles in the overall population. Further exploratory subgroup analysis and multivariable logistic regression analysis revealed a linear relationship between the TyG-BMI index (per 1 SD increased) and MACCEs in the elderly patients (OR = 1.22, 95% CI 1.011-1.467, p = 0.038) and in the female patients (OR = 1.33, 95% CI 1.004-1.764, p = 0.047). The addition of the TyG-BMI index to traditional risk factor models in elderly and female patients did not improve risk prediction for MACCEs.

conclusionA higher TyG-BMI index was proportionally related to an increased incidence of MACCEs in the elderly or female patients. However, the inclusion of the TyG-BMI index did not provide better predictive performance for MACCEs in the elderly, specifically in female patients.

Indexed as

Drug-Eluting StentsPercutaneous Coronary InterventionAgedBiomarkersBlood GlucoseBody Mass IndexFemaleGlucoseHumansRetrospective StudiesRisk AssessmentRisk FactorsTriglyceridesBiomarkersBlood GlucoseGlucoseTriglyceridesCoronary artery diseaseDrug-eluting stentInsulin resistanceMajor adverse cardiac and cerebrovascular eventsPercutaneous coronary interventionTriglyceride glucose-body mass index

Identifiers

PMID36997935
PMCPMC10064664
OpenAlexW4362505789

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.