Evidence map›Paper›PMID 36997876›Full record

ArticleBMC geriatrics2023

Cause-specific excess mortality after hip fracture: the Norwegian Epidemiologic Osteoporosis Studies (NOREPOS).

Kristin Holvik, Christian Lycke Ellingsen, Siri Marie Solbakken, Trine Elisabeth Finnes, Ove Talsnes, Guri Grimnes, Grethe S Tell, Anne-Johanne Søgaard, Haakon E Meyer

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. [Pertrochanteric fractures].Unfallchirurgie (Heidelberg, Germany) · 2026
    Review
  3. Article
  4. Review
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  6. Optimizing Surgical Strategies for Elderly Patients With Femoral Neck Fracture: The Critical Role of Comorbidities.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
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  13. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Kristin HolvikDepartment of Physical Health and Ageing, Norwegian Institute of Public Health, P. O. Box 222, Skøyen, Oslo, 0213, Norway. kristin.holvik@fhi.no.
Christian Lycke EllingsenDepartment of Pathology, Stavanger University Hospital, Stavanger, Norway.
Siri Marie SolbakkenDepartment of Physical Health and Ageing, Norwegian Institute of Public Health, P. O. Box 222, Skøyen, Oslo, 0213, Norway.
Trine Elisabeth FinnesDepartment of Endocrinology, Innlandet Hospital Trust, Hamar, Norway.
Ove TalsnesDepartment of Endocrinology, Oslo University Hospital, Oslo, Norway.
Guri GrimnesDepartment of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway.
Grethe S TellDepartment of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Anne-Johanne SøgaardDepartment of Physical Health and Ageing, Norwegian Institute of Public Health, P. O. Box 222, Skøyen, Oslo, 0213, Norway.
Haakon E MeyerDepartment of Physical Health and Ageing, Norwegian Institute of Public Health, P. O. Box 222, Skøyen, Oslo, 0213, Norway.
Norwegian Institute of Public Health · NOOslo University Hospital · NOStavanger University Hospital · NOUniversity Hospital of North Norway · NOUniversity of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInformation on cause of death may help appraise the degree to which the high excess mortality after hip fracture reflects pre-existing comorbidities or the injury itself. We aimed to describe causes of death and cause-specific excess mortality through the first year after hip fracture.

methodsFor studying the distribution of causes of death by time after hip fracture, we calculated age-adjusted cause-specific mortality at 1, 3, 6 and 12 months in patients hospitalized with hip fracture in Norway 1999-2016. Underlying causes of death were obtained from the Norwegian Cause of Death Registry and grouped by the European Shortlist for Causes of Death. For estimating excess mortality, we performed flexible parametric survival analyses comparing mortality hazard in patients with hip fracture (2002-2017) with that of age- and sex matched controls drawn from the Population and Housing Census 2001.

resultsOf 146,132 Norwegians with a first hip fracture, a total of 35,498 (24.3%) died within one year. By 30 days post-fracture, external causes (mainly the fall causing the fracture) were the underlying cause for 53.8% of deaths, followed by circulatory diseases (19.8%), neoplasms (9.4%), respiratory diseases (5.7%), mental and behavioural disorders (2.0%) and diseases of the nervous system (1.3%). By one-year post-fracture, external causes and circulatory diseases together accounted for approximately half of deaths (26.1% and 27.0%, respectively). In the period 2002-2017, cause-specific one-year relative mortality hazard in hip fracture patients vs. population controls ranged from 1.5 for circulatory diseases to 2.5 for diseases of the nervous system in women, and correspondingly, from 2.4 to 5.3 in men.

conclusionsHip fractures entail high excess mortality from all major causes of death. However, the traumatic injury of a hip fracture is the most frequently reported underlying cause of death among older patients who survive less than one year after their fracture.

Indexed as

Cardiovascular DiseasesHip FracturesOsteoporosisComorbidityFemaleHumansMaleNorwayRisk FactorsCauses of deathExcess mortalityHip fractureNorwayRegistry-based epidemiology

Identifiers

PMID36997876
PMCPMC10064567
OpenAlexW4362506353

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.