Evidence map›Paper›PMID 36997763›Full record

ArticleInflammation2023

Dehydration Accelerates Cytogenesis and Cyst Growth in Pkd1

Yang Yang, Jie Zhou, Dongjuan Zhang, Jiayi Lv, Meihan Chen, Chao Wang, Minghui Song, Fagui He, Shuwei Song, Changlin Mei

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Lactate-Mediated Lysine Lactylation in Renal Fibrosis: Current Progress and Challenges.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Yang YangDepartment of Nephrology, The 981th Hospital of Joint Logistic Support Force of Chinese People's Liberation Army, Puning Road, No.3, Shuangqiao District, Chengde, China. yybjzy@163.com.
Jie ZhouDepartment of Nephrology, Affiliated Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Dongjuan ZhangDepartment of Nephrology, The 981th Hospital of Joint Logistic Support Force of Chinese People's Liberation Army, Puning Road, No.3, Shuangqiao District, Chengde, China.
Jiayi LvKidney Institution of the Chinese People's Liberation Army, Changzheng Hospital, The Navy Military Medical University, Fengyang Road, No.415, Huangpu District, Shanghai, China.
Meihan ChenDepartment of Nephrology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Chao WangKidney Diagnostic and Therapeutic Center of People's Liberation Army, Beidaihe Rehabilitation and Recuperation Center of the Chinese People's Liberation Army, Qinhuangdao, China.
Minghui SongClinical Laboratory, Hainan Hospital of General Hospital of Chinese People's Liberation Army, Sanya, China.
Fagui HeDepartment of Nephrology, The 981th Hospital of Joint Logistic Support Force of Chinese People's Liberation Army, Puning Road, No.3, Shuangqiao District, Chengde, China.
Shuwei SongKidney Institution of the Chinese People's Liberation Army, Changzheng Hospital, The Navy Military Medical University, Fengyang Road, No.415, Huangpu District, Shanghai, China.
Changlin MeiKidney Institution of the Chinese People's Liberation Army, Changzheng Hospital, The Navy Military Medical University, Fengyang Road, No.415, Huangpu District, Shanghai, China. chlmei1954@126.com.
Chinese People's Liberation Army · CNPeople's Liberation Army 401 Hospital · CNSecond Military Medical University · CNHainan Branch of People's Liberation Army General Hospital · CNShanghai University of Traditional Chinese Medicine · CNTongji University · CN

Funding

the 13th Five-Year Key Plan for the Military Medical Scientific Research Project CBJ14L016The National Natural Science Foundation of China 81700579, 81670612
6 · The paper itself

Abstract

Adult autosomal dominant polycystic kidney disease (ADPKD) has been shown to be related as a "third hit" to the occurrence of acute or chronic kidney injury. Here, we examined whether dehydration, as a common kidney risk factor, could cause cystogenesis in chronic-onset Pkd1

Indexed as

CystsMacrophage ActivationPolycystic Kidney DiseasesAnimalsDehydrationDisease Models, AnimalKidneyMacrophagesMiceadult autosomal dominant polycystic kidney diseasedehydrationmacrophagemetabolism.

Identifiers

PMID36997763
OpenAlexW4361244476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.