Evidence map›Paper›PMID 36997639›Full record

ArticleScientific reports2023

Diagnostic ability of macular microvasculature with swept-source OCT angiography for highly myopic glaucoma using deep learning.

Yun Jeong Lee, Sukkyu Sun, Young Kook Kim, Jin Wook Jeoung, Ki Ho Park

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Widefield OCT angiography.Progress in retinal and eye research · 2025
    Review
  6. Review
  7. Advances in OCT Angiography.Translational vision science & technology · 2025
    Review
  8. Observational
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yun Jeong LeeDepartment of Ophthalmology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Sukkyu SunBiomedical Research Institute, Seoul National University Hospital, Seoul, Korea.
Young Kook KimDepartment of Ophthalmology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Jin Wook JeoungDepartment of Ophthalmology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Ki Ho ParkDepartment of Ophthalmology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea. kihopark@snu.ac.kr.
Seoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macular OCT angiography (OCTA) measurements have been reported to be useful for glaucoma diagnostics. However, research on highly myopic glaucoma is lacking, and the diagnostic value of macular OCTA measurements versus OCT parameters remains inconclusive. We aimed to evaluate the diagnostic ability of the macular microvasculature assessed with OCTA for highly myopic glaucoma and to compare it with that of macular thickness parameters, using deep learning (DL). A DL model was trained, validated and tested using 260 pairs of macular OCTA and OCT images from 260 eyes (203 eyes with highly myopic glaucoma, 57 eyes with healthy high myopia). The DL model achieved an AUC of 0.946 with the OCTA superficial capillary plexus (SCP) images, which was comparable to that with the OCT GCL+ (ganglion cell layer + inner plexiform layer; AUC, 0.982; P = 0.268) or OCT GCL++ (retinal nerve fiber layer + ganglion cell layer + inner plexiform layer) images (AUC, 0.997; P = 0.101), and significantly superior to that with the OCTA deep capillary plexus images (AUC, 0.779; P = 0.028). The DL model with macular OCTA SCP images demonstrated excellent and comparable diagnostic ability to that with macular OCT images in highly myopic glaucoma, which suggests macular OCTA microvasculature could serve as a potential biomarker for glaucoma diagnosis in high myopia.

Indexed as

Deep LearningGlaucomaMyopiaAngiographyHumansMicrovesselsRetinal Ganglion CellsTomography, Optical Coherence

Identifiers

PMID36997639
PMCPMC10063664
OpenAlexW4361273829

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.