Evidence map›Paper›PMID 36997627›Full record

ArticleScientific reports2023

Hyperpolarized δ-[1-

Noriaki Minami, Donghyun Hong, Celine Taglang, Georgios Batsios, Anne Marie Gillespie, Pavithra Viswanath, Nicholas Stevers, Carter J Barger, Joseph F Costello, Sabrina M Ronen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Quo Vadis HyperpolarizedZeitschrift fur medizinische Physik · 2025
    Review
  2. [Research Progress in Imaging Investigation of TERT Promoter Mutations in Gliomas].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Noriaki Minami *Department of Radiology and Biomedical Imaging, University of California San Francisco, 1700 4th Street, San Francisco, CA, 94158, USA.
Donghyun Hong *Department of Radiology and Biomedical Imaging, University of California San Francisco, 1700 4th Street, San Francisco, CA, 94158, USA.
Celine TaglangDepartment of Radiology and Biomedical Imaging, University of California San Francisco, 1700 4th Street, San Francisco, CA, 94158, USA.
Georgios BatsiosDepartment of Radiology and Biomedical Imaging, University of California San Francisco, 1700 4th Street, San Francisco, CA, 94158, USA.
Anne Marie GillespieDepartment of Radiology and Biomedical Imaging, University of California San Francisco, 1700 4th Street, San Francisco, CA, 94158, USA.
Pavithra ViswanathDepartment of Radiology and Biomedical Imaging, University of California San Francisco, 1700 4th Street, San Francisco, CA, 94158, USA.
Nicholas SteversDepartment of Neurological Surgery, University of California, San Francisco, USA.
Carter J BargerDepartment of Neurological Surgery, University of California, San Francisco, USA.
Joseph F CostelloDepartment of Neurological Surgery, University of California, San Francisco, USA.
Sabrina M RonenDepartment of Radiology and Biomedical Imaging, University of California San Francisco, 1700 4th Street, San Francisco, CA, 94158, USA. sabrina.ronen@ucsf.edu.
University of California System · USUniversity of California, San Francisco · USNeurological Surgery · US

Funding

Tissue CoreP50CA097257 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Susan M Chang · 2002 to 2026
$57.4M
Project 4: Multi-modality Metabolic Imaging for Monitoring Molecular Sub-types of GliomaP01CA118816 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Susan M Chang, Janine Marie Lupo · 2007 to 2026
$44.7M
TR&D3: Open-Source Tools for Processing Hyperpolarized MR DataP41EB013598 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Daniel B Vigneron · 2011 to 2026
$19.9M
Metabolic Reprogramming in Brain TumorsR01CA172845 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RONEN, SABRINA MIRIAM · 2013 to 2022
$6.3M
Metabolic Imaging of Brain Tumor Response to TherapyR01CA197254 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RONEN, SABRINA MIRIAM · 2016 to 2020
$3.2M
Identification of a GABP Feedback Loop and its Role in Tumor Cell ImmortalityF31CA254067 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVERS, NICHOLAS OLIVER · 2020 to 2022
$125k
NCI NIH HHS F31 CA254067NCI NIH HHS P01 CA118816NCI NIH HHS P50 CA097257NCI NIH HHS R01 CA172845NCI NIH HHS R01 CA197254NIBIB NIH HHS P41 EB013598
6 · The paper itself

Abstract

TERT promoter mutations are a hallmark of glioblastoma (GBM). Accordingly, TERT and GABPB1, a subunit of the upstream mutant TERT promoter transcription factor GABP, are being considered as promising therapeutic targets in GBM. We recently reported that the expression of TERT or GABP1 modulates flux via the pentose phosphate pathway (PPP). Here, we investigated whether

Indexed as

Brain NeoplasmsGlioblastomaTelomeraseDiagnostic ImagingGA-Binding Protein Transcription FactorGluconatesHumansLactonesMagnetic Resonance Spectroscopybeta-glucono-1,5-lactoneGA-Binding Protein Transcription FactorGABPB1 protein, humanGluconatesLactonesTelomeraseTERT protein, human

Identifiers

PMID36997627
PMCPMC10063634
OpenAlexW4361279760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.